{"product_id":"anti-hla-dmb-rabbit-monoclonal-antibody-bha21010212","title":"Anti-HLA DMB Rabbit Monoclonal Antibody","description":"\u003cp\u003eBoster Bio Anti-HLA DMB Rabbit Monoclonal Antibody catalog # M03526. Tested in WB, Flow Cytometry applications. This antibody reacts with Human.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eProtein\u003c\/strong\u003e: T-cell surface glycoprotein CD3 zeta chain | \u003cstrong\u003eGene\u003c\/strong\u003e: Bcl2-associated agonist of cell death | \u003cstrong\u003eTarget\u003c\/strong\u003e: HLA-DMB | \u003cstrong\u003eFunction\u003c\/strong\u003e: Promotes cell death. Successfully competes for the binding to Bcl-X (L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X (L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways. . | \u003cstrong\u003eResearch areas\u003c\/strong\u003e: Neurology Process,Neuroscience,Alzheimer's Disease,Neurodegenerative Disease\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHost\u003c\/strong\u003e: Rabbit | \u003cstrong\u003eClonality\/Clone\u003c\/strong\u003e: Monoclonal \/ Clone: 27H21 | \u003cstrong\u003eIsotype\u003c\/strong\u003e: IgG | \u003cstrong\u003eReactivity\u003c\/strong\u003e: Human | \u003cstrong\u003eImmunogen\u003c\/strong\u003e: A synthesized peptide derived from human HLA DMB | \u003cstrong\u003eConcentration\u003c\/strong\u003e: 0.5mg\/ml | \u003cstrong\u003ePurification\u003c\/strong\u003e: Affinity-chromatography\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplications\u003c\/strong\u003e: WB, ICC, FC\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eObserved MW\u003c\/strong\u003e: 29 kDa | \u003cstrong\u003eCalculated MW\u003c\/strong\u003e: 18392 MW\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCellular localization\u003c\/strong\u003e: Mitochondrion outer membrane. Cytoplasm . Colocalizes with HIF3A in the cytoplasm (By similarity). Upon phosphorylation, locates to the cytoplasm. .\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTissue details\u003c\/strong\u003e: Expressed in a wide variety of tissues.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eStatus\u003c\/strong\u003e: Active\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"100 uL\/vial \/ Unconjugated","offer_id":53072123036013,"sku":"M03526","price":370.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/m03526-wb.jpg?v=1772621946","url":"https:\/\/www.ebiohippo.com\/products\/anti-hla-dmb-rabbit-monoclonal-antibody-bha21010212","provider":"BioHippo","version":"1.0","type":"link"}