{"product_id":"anti-human-app-amyloid-beta-antibody-m266-bha21405627","title":"Anti-Human APP\/Amyloid beta Antibody (m266)","description":"\u003cp\u003e\u003cstrong\u003eOverview\u003c\/strong\u003e\u003cbr\u003eAntibody against APP\/Amyloid beta (Protease nexin-II) for research detection of protein expression and localization.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTarget biology\u003c\/strong\u003e\u003cbr\u003eProtease nexin-II is a protease\/peptidase that cleaves protein substrates to regulate maturation, signaling or degradation. Protease activity can drive pathway activation (e.g., zymogen processing) and is often studied in inflammation, apoptosis and extracellular matrix remodeling.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eExpected localization\u003c\/strong\u003e\u003cbr\u003eLocalization depends on protease class (cytosolic, lysosomal, secreted, or membrane-associated).\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch context\u003c\/strong\u003e\u003cbr\u003eThis target is frequently studied in the context of \u003cem\u003eNeuroscience\u003c\/em\u003e research. Application suitability (e.g., ELISA) is indicated in the specifications; conditions should be optimized by titration. Species reactivity information is provided in the specifications (reported: Human).\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eRecommended experimental notes\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\u003cli\u003eFor ELISA, ensure capture\/detection antibody compatibility and run a standard curve; verify sample matrix effects with spike-and-recovery and dilution linearity.\u003c\/li\u003e\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eControls \u0026amp; interpretation\u003c\/strong\u003e\u003cbr\u003eWhere possible, confirm specificity using genetic perturbation (KO\/KD\/CRISPR), peptide competition (if applicable), or an orthogonal readout. Include a negative control sample expected to express low\/none of APP\/Amyloid beta, and a positive control sample known to express APP\/Amyloid beta.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eFor research use only. Not for diagnostic procedures.\u003c\/em\u003e\u003c\/p\u003e","brand":"Biohippo Inc","offers":[{"title":"50 ug","offer_id":53036933284205,"sku":"HY235103-50UG","price":191.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53037540409709,"sku":"HY235103-100UG","price":370.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53037540442477,"sku":"HY235103-1MG","price":1858.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/HY235103-SDSPAGE-1.jpg?v=1771746084","url":"https:\/\/www.ebiohippo.com\/products\/anti-human-app-amyloid-beta-antibody-m266-bha21405627","provider":"BioHippo","version":"1.0","type":"link"}