{"product_id":"anti-human-cd153-tnfsf8-polyclonal-antibody-bha21402000","title":"Anti-Human CD153\/TNFSF8 Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eOverview\u003c\/strong\u003e\u003cbr\u003e\nAnti-Human CD153\/TNFSF8 Polyclonal Antibody targets \u003cstrong\u003eTNFSF8\u003c\/strong\u003e (Tumor necrosis factor ligand superfamily member 8). Commonly used in ELISA, IHC, WB workflows. Research contexts include Immunology \u0026amp; Inflammation.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eAlso known as:\u003c\/strong\u003e Tumor necrosis factor ligand superfamily member 8, TNFSF8, CD153, CD30-L, CD30L, CD30LG, CD30 ligand.\u003c\/p\u003e\n\n\u003ch3\u003eTarget biology\u003c\/h3\u003e\n\u003cp\u003eTNFSF8 is a TNF ligand superfamily cytokine best known as the CD30 ligand (often referred to as CD30L or CD153). It is typically induced on activated immune cells and engages CD30 (TNFRSF8) to modulate costimulatory signaling, cytokine programs, and immune-cell interactions. These features make TNFSF8 useful for studying immune activation and CD30–CD30L biology. Common names in the literature include: Tumor necrosis factor ligand superfamily member 8, TNFSF8, CD153, CD30-L, CD30L, CD30LG. Typical localization reported for this class of target is cell surface \/ secreted signaling interface.\u003c\/p\u003e\n\n\u003ch3\u003eHow this antibody helps\u003c\/h3\u003e\n\u003cp\u003eAs a polyclonal reagent, this antibody can provide enhanced sensitivity through multi-epitope recognition. Use it to profile target expression and localization and to compare signal across conditions with matched controls.\u003c\/p\u003e\n\n\u003ch3\u003eAntigen \/ immunogen context\u003c\/h3\u003e\u003cp\u003eE. coli - derived recombinant Human CD153\/TNFSF8 (Leu60-Ile227).\u003c\/p\u003e\n\n\u003ch3\u003eRecommended experimental notes\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eTitrate the antibody to optimize signal-to-noise for your specific sample type and detection system.\u003c\/li\u003e\n\u003cli\u003eUse appropriate positive and negative controls (e.g., target-high vs target-low samples, KO\/KD where available).\u003c\/li\u003e\n\u003cli\u003eFor Western blotting, include fresh protease inhibitors and confirm the dominant band at the expected molecular weight; additional bands may reflect isoforms or processing.\u003c\/li\u003e\n\u003cli\u003eFor IHC, optimize fixation and antigen retrieval (buffer\/pH\/heat) and include isotype\/secondary-only controls to assess background.\u003c\/li\u003e\n\u003cli\u003eFor ELISA, optimize coating\/capture conditions and validate dynamic range with appropriate standards or reference samples.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eAdditional notes\u003c\/h3\u003e\u003cp\u003eFor research use only.\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eFor research use only. Not for diagnostic procedures.\u003c\/em\u003e\u003c\/p\u003e","brand":"Biohippo Inc","offers":[{"title":"50 ug","offer_id":53036810862957,"sku":"HW454014-50UG","price":100.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53037394198893,"sku":"HW454014-100UG","price":160.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/HW454014-abinscience-WB-1.jpg?v=1771743858","url":"https:\/\/www.ebiohippo.com\/products\/anti-human-cd153-tnfsf8-polyclonal-antibody-bha21402000","provider":"BioHippo","version":"1.0","type":"link"}