{"product_id":"anti-human-cd182-cxcr2-nanobody-saa1360-bha21408040","title":"Anti-Human CD182\/CXCR2 Nanobody (SAA1360)","description":"\u003cp\u003e\u003cstrong\u003eOverview\u003c\/strong\u003e\u003cbr\u003e\nAnti-Human CD182\/CXCR2 Nanobody (SAA1360) targets \u003cstrong\u003eCD182\/CXCR2\u003c\/strong\u003e (C-X-C chemokine receptor type 2). Frequently used across ELISA, IF, IP, WB workflows, depending on experimental design and sample type. This antibody is suited for workflows commonly used in Immunology \u0026amp; Inflammation research.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eAlso known as:\u003c\/strong\u003e C-X-C chemokine receptor type 2, High affinity interleukin-8 receptor B, IL-8 receptor type 2, GRO\/MGSA receptor, IL-8R B, CXCR-2, CXC-R2, CDw128b.\u003c\/p\u003e\n\n\u003ch3\u003eTarget biology\u003c\/h3\u003e\n\u003cp\u003eCD182\/CXCR2 (C-X-C chemokine receptor type 2) encodes a receptor or receptor subunit involved in sensing extracellular or cell-surface cues and relaying signals to intracellular pathways. Receptor availability at the cell surface and activation state can vary with differentiation and stimulation conditions. Common alternative names and symbols used in the literature include: High affinity interleukin-8 receptor B, IL-8 receptor type 2, GRO\/MGSA receptor, IL-8R B, CXCR-2, CXC-R2, CDw128b. Based on the annotated name\/class, the target is most often associated with secreted \/ extracellular localization, though this can vary by model system.\u003c\/p\u003e\n\n\u003ch3\u003eHow this antibody helps\u003c\/h3\u003e\n\u003cp\u003eAs a monoclonal reagent, this antibody is designed for clone-to-clone consistency and epitope-focused recognition. For best performance, interpret signal in the context of appropriate biological controls and orthogonal readouts when available.\u003c\/p\u003e\n\n\u003ch3\u003eRecommended experimental notes\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eTitrate the antibody to optimize signal-to-noise for your specific sample type and detection system.\u003c\/li\u003e\n\u003cli\u003eUse appropriate positive and negative controls (e.g., target-high vs target-low samples, KO\/KD where available).\u003c\/li\u003e\n\u003cli\u003eFor Western blotting, use fresh protease (and phosphatase, if relevant) inhibitors and confirm the primary band at the expected molecular weight; additional bands may reflect isoforms or processing.\u003c\/li\u003e\n\u003cli\u003eFor IF\/ICC, test fixation (PFA vs methanol) and permeabilization conditions to preserve epitope accessibility while minimizing background.\u003c\/li\u003e\n\u003cli\u003eFor immunoprecipitation, use gentle lysis conditions, maintain cold temperatures, and validate enrichment relative to an isotype control.\u003c\/li\u003e\n\u003cli\u003eFor ELISA, optimize capture\/detection pairing and run a standard curve in matrix-matched diluent when possible.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eAdditional notes\u003c\/h3\u003e\u003cp\u003eFor research use only.\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eFor research use only. Not for diagnostic procedures.\u003c\/em\u003e\u003c\/p\u003e","brand":"Biohippo Inc","offers":[{"title":"50 ug","offer_id":53037014876525,"sku":"HB243013-50UG","price":191.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53037703922029,"sku":"HB243013-100UG","price":370.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53037703954797,"sku":"HB243013-1MG","price":1858.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/HB243013-SDS-PAGE-1.jpg?v=1771747603","url":"https:\/\/www.ebiohippo.com\/products\/anti-human-cd182-cxcr2-nanobody-saa1360-bha21408040","provider":"BioHippo","version":"1.0","type":"link"}