{"product_id":"anti-human-cybb-nox2-antibody-saa0847-bha21412515","title":"Anti-Human CYBB\/NOX2 Antibody (SAA0847)","description":"\u003cp\u003e\u003cstrong\u003eOverview\u003c\/strong\u003e\u003cbr\u003e\nAnti-Human CYBB\/NOX2 Antibody (SAA0847) targets \u003cstrong\u003eCYBB\u003c\/strong\u003e (Superoxide-generating NADPH oxidase heavy chain subunit). Frequently used across FCM, IP, WB workflows, depending on experimental design and sample type. This antibody is suited for workflows commonly used in Molecular \u0026amp; Cellular Biology research.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eAlso known as:\u003c\/strong\u003e Superoxide-generating NADPH oxidase heavy chain subunit, Heme-binding membrane glycoprotein gp91phox, Neutrophil cytochrome b 91 kDa polypeptide, Cytochrome b(558) subunit beta, Cytochrome b558 subunit beta, Cytochrome b-245 heavy chain, p22 phagocyte B-cytochrome, NADPH oxidase 2, CGD91-phox, gp91-phox.\u003c\/p\u003e\n\n\u003ch3\u003eTarget biology\u003c\/h3\u003e\n\u003cp\u003eCYBB (Superoxide-generating NADPH oxidase heavy chain subunit) is a pathogen-derived antigen commonly used to detect infection, antigen expression, or immune responses in research assays. Envelope\/glycoprotein antigens are often surface-exposed and may be assessed for expression, trafficking, and antibody recognition in cell-based systems. Assay performance can depend on native conformation, glycosylation, and sample preparation conditions. Common alternative names and symbols used in the literature include: Heme-binding membrane glycoprotein gp91phox, Neutrophil cytochrome b 91 kDa polypeptide, Cytochrome b(558) subunit beta, Cytochrome b558 subunit beta, Cytochrome b-245 heavy chain, p22 phagocyte B-cytochrome, NADPH oxidase 2, CGD91-phox, gp91-phox, gp91-1. Based on the annotated name\/class, the target is most often associated with plasma membrane and\/or intracellular membranes localization, though this can vary by model system.\u003c\/p\u003e\n\n\u003ch3\u003eHow this antibody helps\u003c\/h3\u003e\n\u003cp\u003eAs a monoclonal reagent, this antibody is designed for clone-to-clone consistency and epitope-focused recognition. For best performance, interpret signal in the context of appropriate biological controls and orthogonal readouts when available.\u003c\/p\u003e\n\n\u003ch3\u003eRecommended experimental notes\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eTitrate the antibody to optimize signal-to-noise for your specific sample type and detection system.\u003c\/li\u003e\n\u003cli\u003eUse appropriate positive and negative controls (e.g., target-high vs target-low samples, KO\/KD where available).\u003c\/li\u003e\n\u003cli\u003eFor Western blotting, use fresh protease (and phosphatase, if relevant) inhibitors and confirm the primary band at the expected molecular weight; additional bands may reflect isoforms or processing.\u003c\/li\u003e\n\u003cli\u003eFor immunoprecipitation, use gentle lysis conditions, maintain cold temperatures, and validate enrichment relative to an isotype control.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e\u003cem\u003eFor research use only. Not for diagnostic procedures.\u003c\/em\u003e\u003c\/p\u003e","brand":"Biohippo Inc","offers":[{"title":"100 ug","offer_id":53037162332525,"sku":"HY448107-100UG","price":370.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/HY448107-SDS-PAGE-1.jpg?v=1771748955","url":"https:\/\/www.ebiohippo.com\/products\/anti-human-cybb-nox2-antibody-saa0847-bha21412515","provider":"BioHippo","version":"1.0","type":"link"}