{"product_id":"anti-human-dsg1-3-antibody-saa0841-bha21412520","title":"Anti-Human DSG1\/3 Antibody (SAA0841)","description":"\u003cp\u003e\u003cstrong\u003eOverview\u003c\/strong\u003e\u003cbr\u003e\nAnti-Human DSG1\/3 Antibody (SAA0841) targets \u003cstrong\u003eDSG1\u003c\/strong\u003e (130 kDa pemphigus vulgaris antigen). Frequently used across ELISA, FCM, IF workflows, depending on experimental design and sample type. This antibody is suited for workflows commonly used in ECM \u0026amp; Cell Adhesion research.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eAlso known as:\u003c\/strong\u003e 130 kDa pemphigus vulgaris antigen, Cadherin family member 4, Cadherin family member 6, Desmosomal glycoprotein 1, Pemphigus foliaceus antigen, Desmoglein-1, Desmoglein-3, CDHF4, CDHF6, DSG3.\u003c\/p\u003e\n\n\u003ch3\u003eTarget biology\u003c\/h3\u003e\n\u003cp\u003eDSG1 (130 kDa pemphigus vulgaris antigen) is a pathogen-derived antigen commonly used to detect infection, antigen expression, or immune responses in research assays. Envelope\/glycoprotein antigens are often surface-exposed and may be assessed for expression, trafficking, and antibody recognition in cell-based systems. Assay performance can depend on native conformation, glycosylation, and sample preparation conditions. Common alternative names and symbols used in the literature include: Cadherin family member 4, Cadherin family member 6, Desmosomal glycoprotein 1, Pemphigus foliaceus antigen, Desmoglein-1, Desmoglein-3, CDHF4, CDHF6, DSG3, DGI. Based on the annotated name\/class, the target is most often associated with plasma membrane and\/or intracellular membranes localization, though this can vary by model system.\u003c\/p\u003e\n\n\u003ch3\u003eHow this antibody helps\u003c\/h3\u003e\n\u003cp\u003eAs a monoclonal reagent, this antibody is designed for clone-to-clone consistency and epitope-focused recognition. For best performance, interpret signal in the context of appropriate biological controls and orthogonal readouts when available.\u003c\/p\u003e\n\n\u003ch3\u003eRecommended experimental notes\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eTitrate the antibody to optimize signal-to-noise for your specific sample type and detection system.\u003c\/li\u003e\n\u003cli\u003eUse appropriate positive and negative controls (e.g., target-high vs target-low samples, KO\/KD where available).\u003c\/li\u003e\n\u003cli\u003eFor IF\/ICC, test fixation (PFA vs methanol) and permeabilization conditions to preserve epitope accessibility while minimizing background.\u003c\/li\u003e\n\u003cli\u003eFor ELISA, optimize capture\/detection pairing and run a standard curve in matrix-matched diluent when possible.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e\u003cem\u003eFor research use only. Not for diagnostic procedures.\u003c\/em\u003e\u003c\/p\u003e","brand":"Biohippo Inc","offers":[{"title":"100 ug","offer_id":53037162004845,"sku":"HX965107-100UG","price":370.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/HX965107-SDS-PAGE-1.jpg?v=1771748910","url":"https:\/\/www.ebiohippo.com\/products\/anti-human-dsg1-3-antibody-saa0841-bha21412520","provider":"BioHippo","version":"1.0","type":"link"}