{"product_id":"anti-human-igg1-rabbit-monoclonal-antibody-bha21010195","title":"Anti-Human IgG1 Rabbit Monoclonal Antibody","description":"\u003cp\u003eBoster Bio Anti-Human IgG1 Rabbit Monoclonal Antibody catalog # M04575-6. Tested in WB application. This antibody reacts with Human.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eProtein\u003c\/strong\u003e: T-cell surface glycoprotein CD3 zeta chain | \u003cstrong\u003eGene\u003c\/strong\u003e: Ig gamma-1 chain C region | \u003cstrong\u003eTarget\u003c\/strong\u003e: IGHG1 | \u003cstrong\u003eFunction\u003c\/strong\u003e: Component of the anaphase promoting complex\/cyclosome (APC\/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC\/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. . | \u003cstrong\u003eResearch areas\u003c\/strong\u003e: Immunoglobulins,Immunology\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHost\u003c\/strong\u003e: Rabbit | \u003cstrong\u003eClonality\/Clone\u003c\/strong\u003e: Monoclonal \/ Clone: 27I03 | \u003cstrong\u003eIsotype\u003c\/strong\u003e: IgG | \u003cstrong\u003eReactivity\u003c\/strong\u003e: Human | \u003cstrong\u003eImmunogen\u003c\/strong\u003e: A synthesized peptide derived from human IgG1 | \u003cstrong\u003eConcentration\u003c\/strong\u003e: 0.5mg\/ml | \u003cstrong\u003ePurification\u003c\/strong\u003e: Affinity-chromatography\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplications\u003c\/strong\u003e: WB\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eObserved MW\u003c\/strong\u003e: 52 kDa | \u003cstrong\u003eCalculated MW\u003c\/strong\u003e: 36106 MW\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCellular localization\u003c\/strong\u003e: Secreted.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTissue details\u003c\/strong\u003e: According to PubMed:9858585, highest levels of expression in adult testis, thymus and brain. Lower levels in placenta, spleen and colon. Consistently elevated levels in tumor- derived cells compared to non-transformed proliferating cells. According to PubMed:9840927: low levels in thymus, prostate, brain, skeletal muscle, and kidney. Elevated levels in lung. According to PubMed:9840943 highly expressed in testis, placenta, thymus and brain. In a lesser extent in small intestine and colon.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eStatus\u003c\/strong\u003e: Active\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"100 uL\/vial \/ Unconjugated","offer_id":53072119169389,"sku":"M04575-6","price":370.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/m04575-6-wb.jpg?v=1772621948","url":"https:\/\/www.ebiohippo.com\/products\/anti-human-igg1-rabbit-monoclonal-antibody-bha21010195","provider":"BioHippo","version":"1.0","type":"link"}