{"product_id":"anti-human-kdm6b-ip-antibody-saa0207-bha21405232","title":"Anti-Human KDM6B IP Antibody (SAA0207)","description":"\u003cp\u003e\u003cstrong\u003eOverview\u003c\/strong\u003e\u003cbr\u003eAntibody against KDM6B IP (Jumonji domain-containing protein 3) for research detection of protein expression and localization.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTarget biology\u003c\/strong\u003e\u003cbr\u003eKDM6B is commonly studied as part of epigenetic and chromatin-regulatory machinery that controls transcriptional accessibility through histone modification or chromatin remodeling. These regulators influence differentiation, DNA repair and oncogenic transcriptional programs.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eExpected localization\u003c\/strong\u003e\u003cbr\u003eTypically nuclear, often enriched in chromatin-associated complexes.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch context\u003c\/strong\u003e\u003cbr\u003eThis target is frequently studied in the context of \u003cem\u003eGene Expression \u0026amp; Epigenetics\u003c\/em\u003e research. Application suitability (e.g., ELISA, IF, IP) is indicated in the specifications; conditions should be optimized by titration. Species reactivity information is provided in the specifications (reported: Human).\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eRecommended experimental notes\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eFor IF\/ICC, adjust permeabilization (e.g., mild detergent vs stronger conditions) based on expected localization; include secondary-only and isotype controls for background.\u003c\/li\u003e\n\u003cli\u003eFor IP, use gentle lysis to preserve complexes and include an IgG control; validate enrichment by immunoblot or orthogonal detection.\u003c\/li\u003e\n\u003cli\u003eFor ELISA, ensure capture\/detection antibody compatibility and run a standard curve; verify sample matrix effects with spike-and-recovery and dilution linearity.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eControls \u0026amp; interpretation\u003c\/strong\u003e\u003cbr\u003eWhere possible, confirm specificity using genetic perturbation (KO\/KD\/CRISPR), peptide competition (if applicable), or an orthogonal readout. Include a negative control sample expected to express low\/none of KDM6B IP, and a positive control sample known to express KDM6B IP.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eFor research use only. Not for diagnostic procedures.\u003c\/em\u003e\u003c\/p\u003e","brand":"Biohippo Inc","offers":[{"title":"50 ug","offer_id":53036920111469,"sku":"HT282013-50UG","price":191.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53037513212269,"sku":"HT282013-100UG","price":370.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53037513245037,"sku":"HT282013-1MG","price":1858.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/HT282013-SDSPAGE-1.jpg?v=1771745820","url":"https:\/\/www.ebiohippo.com\/products\/anti-human-kdm6b-ip-antibody-saa0207-bha21405232","provider":"BioHippo","version":"1.0","type":"link"}