{"product_id":"anti-human-mapt-tau-phf-tau-nanobody-saa2138-bha21405383","title":"Anti-Human MAPT\/Tau\/PHF-tau Nanobody (SAA2138)","description":"\u003cp\u003e\u003cstrong\u003eOverview\u003c\/strong\u003e\u003cbr\u003eAntibody against MAPT\/Tau\/PHF-tau (Microtubule-associated protein tau) for research detection of protein expression and localization.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTarget biology\u003c\/strong\u003e\u003cbr\u003eMAPT encodes tau, a microtubule-associated protein that stabilizes microtubules in neurons and contributes to axonal transport and cytoskeletal organization. Aberrant phosphorylation and aggregation of tau are hallmark features of several neurodegenerative diseases (tauopathies), and phospho‑tau epitopes are widely used as pathology-associated readouts.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eExpected localization\u003c\/strong\u003e\u003cbr\u003ePredominantly axonal\/cytoskeletal in neurons; can redistribute and accumulate in somatodendritic compartments in disease states.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch context\u003c\/strong\u003e\u003cbr\u003eThis target is frequently studied in the context of \u003cem\u003eNeuroscience\u003c\/em\u003e research. Application suitability (e.g., ELISA) is indicated in the specifications; conditions should be optimized by titration. Species reactivity information is provided in the specifications (reported: Human).\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eRecommended experimental notes\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\u003cli\u003eFor ELISA, ensure capture\/detection antibody compatibility and run a standard curve; verify sample matrix effects with spike-and-recovery and dilution linearity.\u003c\/li\u003e\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eControls \u0026amp; interpretation\u003c\/strong\u003e\u003cbr\u003eWhere possible, confirm specificity using genetic perturbation (KO\/KD\/CRISPR), peptide competition (if applicable), or an orthogonal readout. Include a negative control sample expected to express low\/none of MAPT\/Tau\/PHF-tau, and a positive control sample known to express MAPT\/Tau\/PHF-tau.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eFor research use only. Not for diagnostic procedures.\u003c\/em\u003e\u003c\/p\u003e","brand":"Biohippo Inc","offers":[{"title":"50 ug","offer_id":53036925288813,"sku":"HY086253-50UG","price":191.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53037523272045,"sku":"HY086253-100UG","price":370.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53037523304813,"sku":"HY086253-1MG","price":1858.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/HY086253-SDSPAGE-TF-1.jpg?v=1771745856","url":"https:\/\/www.ebiohippo.com\/products\/anti-human-mapt-tau-phf-tau-nanobody-saa2138-bha21405383","provider":"BioHippo","version":"1.0","type":"link"}