{"product_id":"anti-human-pappa-monoclonal-antibody-1a406-bha21415995","title":"Anti-Human PAPPA Monoclonal Antibody (1A406)","description":"\u003cp\u003e\u003cstrong\u003eOverview\u003c\/strong\u003e\u003cbr\u003e\nAnti-Human PAPPA Monoclonal Antibody (1A406) targets \u003cstrong\u003ePAPPA\u003c\/strong\u003e (Insulin-like growth factor-dependent IGF-binding protein 4 protease). Frequently used across ELISA workflows, depending on experimental design and sample type. This antibody is suited for workflows commonly used in Metabolism \u0026amp; Diabetes research.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eAlso known as:\u003c\/strong\u003e Insulin-like growth factor-dependent IGF-binding protein 4 protease, Pregnancy-associated plasma protein A, IGF-dependent IGFBP-4 protease, Pappalysin-1, IGFBP-4ase, PAPP-A, 3.4.24.79.\u003c\/p\u003e\n\n\u003ch3\u003eTarget biology\u003c\/h3\u003e\n\u003cp\u003ePAPPA (Insulin-like growth factor-dependent IGF-binding protein 4 protease) encodes a protease\/peptidase involved in protein processing or turnover. Protease targets can appear as multiple bands\/fragments depending on processing and sample handling. Common alternative names and symbols used in the literature include: Pregnancy-associated plasma protein A, IGF-dependent IGFBP-4 protease, Pappalysin-1, IGFBP-4ase, PAPP-A, 3.4.24.79. Based on the annotated name\/class, the target is most often associated with secreted \/ extracellular localization, though this can vary by model system.\u003c\/p\u003e\n\n\u003ch3\u003eHow this antibody helps\u003c\/h3\u003e\n\u003cp\u003eAs a monoclonal reagent, this antibody is designed for clone-to-clone consistency and epitope-focused recognition. For best performance, interpret signal in the context of appropriate biological controls and orthogonal readouts when available.\u003c\/p\u003e\n\n\u003ch3\u003eAntigen \/ immunogen context\u003c\/h3\u003e\u003cp\u003eHuman PAPPA Protein.\u003c\/p\u003e\n\n\u003ch3\u003eRecommended experimental notes\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eTitrate the antibody to optimize signal-to-noise for your specific sample type and detection system.\u003c\/li\u003e\n\u003cli\u003eUse appropriate positive and negative controls (e.g., target-high vs target-low samples, KO\/KD where available).\u003c\/li\u003e\n\u003cli\u003eFor ELISA, optimize capture\/detection pairing and run a standard curve in matrix-matched diluent when possible.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eAdditional notes\u003c\/h3\u003e\u003cp\u003eFor research use only.\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eFor research use only. Not for diagnostic procedures.\u003c\/em\u003e\u003c\/p\u003e","brand":"Biohippo Inc","offers":[{"title":"50 ug","offer_id":53037188120941,"sku":"HC474015-50UG","price":194.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53037826834797,"sku":"HC474015-100UG","price":311.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/HC474015-SDS-PAGE-1.jpg?v=1771749400","url":"https:\/\/www.ebiohippo.com\/products\/anti-human-pappa-monoclonal-antibody-1a406-bha21415995","provider":"BioHippo","version":"1.0","type":"link"}