{"product_id":"anti-human-ptk2b-pyk2-antibody-12a10-bha21412388","title":"Anti-Human PTK2B\/PYK2 Antibody (12A10)","description":"\u003cp\u003e\u003cstrong\u003eOverview\u003c\/strong\u003e\u003cbr\u003e\nAnti-Human PTK2B\/PYK2 Antibody (12A10) targets \u003cstrong\u003ePTK2B\u003c\/strong\u003e (Calcium-regulated non-receptor proline-rich tyrosine kinase). Frequently used across FCM workflows, depending on experimental design and sample type. This antibody is suited for workflows commonly used in Cell Signaling research.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eAlso known as:\u003c\/strong\u003e Calcium-regulated non-receptor proline-rich tyrosine kinase, Related adhesion focal tyrosine kinase, Protein-tyrosine kinase 2-beta, Proline-rich tyrosine kinase 2, Calcium-dependent tyrosine kinase, Cell adhesion kinase beta, Focal adhesion kinase 2, FADK 2, CAK-beta, 2.7.10.2.\u003c\/p\u003e\n\n\u003ch3\u003eTarget biology\u003c\/h3\u003e\n\u003cp\u003ePTK2B (Calcium-regulated non-receptor proline-rich tyrosine kinase) encodes a receptor kinase that converts extracellular cues into phosphorylation-driven signaling programs controlling growth, survival, or differentiation. Receptor processing and activation state can affect apparent banding and signal intensity across assays. Common alternative names and symbols used in the literature include: Related adhesion focal tyrosine kinase, Protein-tyrosine kinase 2-beta, Proline-rich tyrosine kinase 2, Calcium-dependent tyrosine kinase, Cell adhesion kinase beta, Focal adhesion kinase 2, FADK 2, CAK-beta, 2.7.10.2, CADTK. Based on the annotated name\/class, the target is most often associated with plasma membrane and\/or intracellular membranes localization, though this can vary by model system.\u003c\/p\u003e\n\n\u003ch3\u003eHow this antibody helps\u003c\/h3\u003e\n\u003cp\u003eAs a monoclonal reagent, this antibody is designed for clone-to-clone consistency and epitope-focused recognition. For best performance, interpret signal in the context of appropriate biological controls and orthogonal readouts when available.\u003c\/p\u003e\n\n\u003ch3\u003eRecommended experimental notes\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eTitrate the antibody to optimize signal-to-noise for your specific sample type and detection system.\u003c\/li\u003e\n\u003cli\u003eUse appropriate positive and negative controls (e.g., target-high vs target-low samples, KO\/KD where available).\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e\u003cem\u003eFor research use only. Not for diagnostic procedures.\u003c\/em\u003e\u003c\/p\u003e","brand":"Biohippo Inc","offers":[{"title":"100 ug","offer_id":53037157187949,"sku":"HC433107-100UG","price":370.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/HC433107-SDS-PAGE-1.gif?v=1771748858","url":"https:\/\/www.ebiohippo.com\/products\/anti-human-ptk2b-pyk2-antibody-12a10-bha21412388","provider":"BioHippo","version":"1.0","type":"link"}