{"product_id":"anti-human-siva1-polyclonal-antibody-bha21402001","title":"Anti-Human SIVA1 Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eOverview\u003c\/strong\u003e\u003cbr\u003e\nAnti-Human SIVA1 Polyclonal Antibody targets \u003cstrong\u003eSIVA1\u003c\/strong\u003e (Apoptosis regulatory protein Siva). Commonly used in ELISA, IHC, WB workflows. Research contexts include Immunology \u0026amp; Inflammation.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eAlso known as:\u003c\/strong\u003e Apoptosis regulatory protein Siva, SIVA1, CD27BP, CD27-binding protein, SIVA.\u003c\/p\u003e\n\n\u003ch3\u003eTarget biology\u003c\/h3\u003e\n\u003cp\u003eSIVA1 (SIVA apoptosis-inducing factor) is an intracellular adaptor protein originally described as a CD27-binding protein and implicated in apoptosis and stress-response signaling. Depending on cell context, SIVA1 has been reported to influence programmed cell death and receptor-linked signaling outputs. Common names in the literature include: Apoptosis regulatory protein Siva, SIVA1, CD27BP, CD27-binding protein, SIVA. Typical localization reported for this class of target is plasma membrane and\/or cell surface.\u003c\/p\u003e\n\n\u003ch3\u003eHow this antibody helps\u003c\/h3\u003e\n\u003cp\u003eAs a polyclonal reagent, this antibody can provide enhanced sensitivity through multi-epitope recognition. Use it to profile target expression and localization and to compare signal across conditions with matched controls.\u003c\/p\u003e\n\n\u003ch3\u003eAntigen \/ immunogen context\u003c\/h3\u003e\u003cp\u003eE. coli - derived recombinant Human SIVA1 (Met1-Thr175).\u003c\/p\u003e\n\n\u003ch3\u003eRecommended experimental notes\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eTitrate the antibody to optimize signal-to-noise for your specific sample type and detection system.\u003c\/li\u003e\n\u003cli\u003eUse appropriate positive and negative controls (e.g., target-high vs target-low samples, KO\/KD where available).\u003c\/li\u003e\n\u003cli\u003eFor Western blotting, include fresh protease inhibitors and confirm the dominant band at the expected molecular weight; additional bands may reflect isoforms or processing.\u003c\/li\u003e\n\u003cli\u003eFor IHC, optimize fixation and antigen retrieval (buffer\/pH\/heat) and include isotype\/secondary-only controls to assess background.\u003c\/li\u003e\n\u003cli\u003eFor ELISA, optimize coating\/capture conditions and validate dynamic range with appropriate standards or reference samples.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eAdditional notes\u003c\/h3\u003e\u003cp\u003eFor research use only.\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eFor research use only. Not for diagnostic procedures.\u003c\/em\u003e\u003c\/p\u003e","brand":"Biohippo Inc","offers":[{"title":"50 ug","offer_id":53036810830189,"sku":"HT095014-50UG","price":100.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53037393969517,"sku":"HT095014-100UG","price":160.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.ebiohippo.com\/products\/anti-human-siva1-polyclonal-antibody-bha21402001","provider":"BioHippo","version":"1.0","type":"link"}