{"product_id":"anti-il21r-antibody-picoband-bha21011517","title":"Anti-IL21R Antibody Picoband®","description":"\u003cp\u003eBoster Bio Anti-IL21R Antibody Picoband® catalog # A00808-1. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eScientific background\u003c\/strong\u003e: The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCross reactivity\u003c\/strong\u003e: No cross-reactivity with other proteins\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eProtein\u003c\/strong\u003e: Interleukin-21 receptor | \u003cstrong\u003eGene\u003c\/strong\u003e: interleukin 21 receptor | \u003cstrong\u003eTarget\u003c\/strong\u003e: IL21R\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHost\u003c\/strong\u003e: Rabbit | \u003cstrong\u003eClonality\/Clone\u003c\/strong\u003e: Polyclonal | \u003cstrong\u003eIsotype\u003c\/strong\u003e: Rabbit IgG | \u003cstrong\u003eReactivity\u003c\/strong\u003e: Human | \u003cstrong\u003eImmunogen\u003c\/strong\u003e: A synthetic peptide corresponding to a sequence in the middle region of human IL21R. Human IL21R shares 78.6% amino acid (aa) sequence identity with mouse IL21R. | \u003cstrong\u003eConcentration\u003c\/strong\u003e: Adding 0.2 ml of distilled water will yield a concentration of 500 μg\/ml. | \u003cstrong\u003ePurification\u003c\/strong\u003e: Immunogen affinity purified.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplications\u003c\/strong\u003e: WB, IHC, ICC, FC, ELISA\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eObserved MW\u003c\/strong\u003e: 70 kDa | \u003cstrong\u003eCalculated MW\u003c\/strong\u003e: 59 kDa\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eStatus\u003c\/strong\u003e: Active\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"100 ug\/vial \/ Unconjugated","offer_id":53072151970157,"sku":"A00808-1","price":370.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Biotin","offer_id":53072261742957,"sku":"A00808-1-Biotin","price":570.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Cy3","offer_id":53072261775725,"sku":"A00808-1-Cy3","price":570.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Fluoro488","offer_id":53072261808493,"sku":"A00808-1-Fluoro488","price":570.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Fluoro550","offer_id":53072261841261,"sku":"A00808-1-Fluoro550","price":570.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Fluoro594","offer_id":53072261874029,"sku":"A00808-1-Fluoro594","price":570.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ FITC","offer_id":53072261906797,"sku":"A00808-1-FITC","price":570.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ HRP","offer_id":53072261939565,"sku":"A00808-1-HRP","price":570.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ APC","offer_id":53072261972333,"sku":"A00808-1-APC","price":820.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ PE","offer_id":53072262005101,"sku":"A00808-1-PE","price":820.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Fluoro647","offer_id":53072262037869,"sku":"A00808-1-Fluoro647","price":670.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Carrier Free","offer_id":53072262070637,"sku":"A00808-1-carrier-free","price":370.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/a00808-1-il21r-primary-antibodies-wb-testing-1.jpg?v=1772695711","url":"https:\/\/www.ebiohippo.com\/products\/anti-il21r-antibody-picoband-bha21011517","provider":"BioHippo","version":"1.0","type":"link"}