{"product_id":"anti-influenza-a-virus-m2-ectodomain-m2e-antibody-fab65-bha21405466","title":"Anti-Influenza A virus M2 ectodomain\/M2e Antibody (Fab65)","description":"\u003cp\u003e\u003cstrong\u003eOverview\u003c\/strong\u003e\u003cbr\u003eAntibody against Influenza A virus M2 ectodomain\/M2e (Proton channel protein M2) for research detection of protein expression and localization.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTarget biology\u003c\/strong\u003e\u003cbr\u003eINFLUENZA encodes an ion channel or channel-associated subunit that regulates cellular excitability, signaling and homeostasis through selective ion conductance. Channel expression and localization are frequently examined in neuroscience, cardiovascular biology and epithelial physiology.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eExpected localization\u003c\/strong\u003e\u003cbr\u003eIntegral membrane protein, commonly localized to the plasma membrane; some channels also localize to intracellular membranes.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch context\u003c\/strong\u003e\u003cbr\u003eThis target is frequently studied in the context of \u003cem\u003eInfectious Disease\u003c\/em\u003e research. Application suitability (e.g., ELISA, IF, WB) is indicated in the specifications; conditions should be optimized by titration. Species reactivity information is provided in the specifications (reported: Influenza A virus (strain A\/Puerto Rico\/8\/1934 H1N1)).\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eRecommended experimental notes\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eFor Western blotting, optimize lysis conditions and include reducing\/non-reducing conditions as appropriate; titrate antibody to balance sensitivity and background.\u003c\/li\u003e\n\u003cli\u003eFor IF\/ICC, adjust permeabilization (e.g., mild detergent vs stronger conditions) based on expected localization; include secondary-only and isotype controls for background.\u003c\/li\u003e\n\u003cli\u003eFor ELISA, ensure capture\/detection antibody compatibility and run a standard curve; verify sample matrix effects with spike-and-recovery and dilution linearity.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eControls \u0026amp; interpretation\u003c\/strong\u003e\u003cbr\u003eWhere possible, confirm specificity using genetic perturbation (KO\/KD\/CRISPR), peptide competition (if applicable), or an orthogonal readout. Include a negative control sample expected to express low\/none of Influenza A virus M2 ectodomain\/M2e, and a positive control sample known to express Influenza A virus M2 ectodomain\/M2e.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eFor research use only. Not for diagnostic procedures.\u003c\/em\u003e\u003c\/p\u003e","brand":"Biohippo Inc","offers":[{"title":"50 ug","offer_id":53036927811949,"sku":"VK736033-50UG","price":191.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53037529497965,"sku":"VK736033-100UG","price":370.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53037529530733,"sku":"VK736033-1MG","price":1858.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/VK736033-SDSPAGE-1.jpg?v=1771745919","url":"https:\/\/www.ebiohippo.com\/products\/anti-influenza-a-virus-m2-ectodomain-m2e-antibody-fab65-bha21405466","provider":"BioHippo","version":"1.0","type":"link"}