{"product_id":"anti-masp1-antibody-picoband-bha21011578","title":"Anti-MASP1 Antibody Picoband®","description":"\u003cp\u003eBoster Bio Anti-MASP1 Antibody Picoband® catalog # A02060-1. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eScientific background\u003c\/strong\u003e: This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCross reactivity\u003c\/strong\u003e: No cross-reactivity with other proteins\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eProtein\u003c\/strong\u003e: Mannan-binding lectin serine protease 1 | \u003cstrong\u003eGene\u003c\/strong\u003e: MBL associated serine protease 1 | \u003cstrong\u003eTarget\u003c\/strong\u003e: MASP1\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHost\u003c\/strong\u003e: Rabbit | \u003cstrong\u003eClonality\/Clone\u003c\/strong\u003e: Polyclonal | \u003cstrong\u003eIsotype\u003c\/strong\u003e: Rabbit IgG | \u003cstrong\u003eReactivity\u003c\/strong\u003e: Human,Mouse,Rat | \u003cstrong\u003eImmunogen\u003c\/strong\u003e: E.coli-derived human MASP1 recombinant protein (Position: R169-E580). Human MASP1 shares 84.5% and 83.3% amino acid (aa) sequence identity with mouse and rat MASP1, respectively. | \u003cstrong\u003eConcentration\u003c\/strong\u003e: Adding 0.2 ml of distilled water will yield a concentration of 500 μg\/ml. | \u003cstrong\u003ePurification\u003c\/strong\u003e: Immunogen affinity purified.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplications\u003c\/strong\u003e: WB, IHC, ICC, FC, ELISA\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eObserved MW\u003c\/strong\u003e: 79 kDa | \u003cstrong\u003eCalculated MW\u003c\/strong\u003e: 79 kDa\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eStatus\u003c\/strong\u003e: Active\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"100 ug\/vial \/ Unconjugated","offer_id":53072152166765,"sku":"A02060-1","price":370.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Biotin","offer_id":53072283369837,"sku":"A02060-1-Biotin","price":570.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Cy3","offer_id":53072283402605,"sku":"A02060-1-Cy3","price":570.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Fluoro488","offer_id":53072283435373,"sku":"A02060-1-Fluoro488","price":570.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Fluoro550","offer_id":53072283468141,"sku":"A02060-1-Fluoro550","price":570.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Fluoro594","offer_id":53072283500909,"sku":"A02060-1-Fluoro594","price":570.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ FITC","offer_id":53072283533677,"sku":"A02060-1-FITC","price":570.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ HRP","offer_id":53072283566445,"sku":"A02060-1-HRP","price":570.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ APC","offer_id":53072283599213,"sku":"A02060-1-APC","price":820.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ PE","offer_id":53072283631981,"sku":"A02060-1-PE","price":820.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Fluoro647","offer_id":53072283664749,"sku":"A02060-1-Fluoro647","price":670.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Carrier Free","offer_id":53072283697517,"sku":"A02060-1-carrier-free","price":370.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/a02060-1-masp1-primary-antibodies-wb-testing-1.jpg?v=1772695723","url":"https:\/\/www.ebiohippo.com\/products\/anti-masp1-antibody-picoband-bha21011578","provider":"BioHippo","version":"1.0","type":"link"}