{"product_id":"anti-mycobacterium-tuberculosis-esxa-esat-6-antibody-saa2172-bha21405362","title":"Anti-Mycobacterium tuberculosis esxA\/ESAT-6 Antibody (SAA2172)","description":"\u003cp\u003e\u003cstrong\u003eOverview\u003c\/strong\u003e\u003cbr\u003eAntibody against Mycobacterium tuberculosis esxA\/ESAT-6 (6 kDa early secretory antigenic target) for research detection of protein expression and localization.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTarget biology\u003c\/strong\u003e\u003cbr\u003eMYCOBACTERIUM TUBERCULOSIS ESXA\/ESAT-6 is a transcription factor or transcriptional regulator that modulates gene-expression programs in response to developmental or environmental cues. These proteins often act downstream of signaling pathways and are assessed for expression level, subcellular localization and pathway activation states.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eExpected localization\u003c\/strong\u003e\u003cbr\u003ePrimarily nuclear when active; many are regulated by cytoplasmic sequestration and stimulus-dependent nuclear import.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch context\u003c\/strong\u003e\u003cbr\u003eThis target is frequently studied in the context of \u003cem\u003eMolecular \u0026amp; Cellular Biology\u003c\/em\u003e research. Application suitability (e.g., ELISA) is indicated in the specifications; conditions should be optimized by titration. Species reactivity information is provided in the specifications (reported: Mycobacterium tuberculosis (strain ATCC 25618 \/ H37Rv)).\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eRecommended experimental notes\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\u003cli\u003eFor ELISA, ensure capture\/detection antibody compatibility and run a standard curve; verify sample matrix effects with spike-and-recovery and dilution linearity.\u003c\/li\u003e\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eControls \u0026amp; interpretation\u003c\/strong\u003e\u003cbr\u003eWhere possible, confirm specificity using genetic perturbation (KO\/KD\/CRISPR), peptide competition (if applicable), or an orthogonal readout. Include a negative control sample expected to express low\/none of Mycobacterium tuberculosis esxA\/ESAT-6, and a positive control sample known to express Mycobacterium tuberculosis esxA\/ESAT-6.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eFor research use only. Not for diagnostic procedures.\u003c\/em\u003e\u003c\/p\u003e","brand":"Biohippo Inc","offers":[{"title":"50 ug","offer_id":53036924600685,"sku":"JN009013-50UG","price":191.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53037522289005,"sku":"JN009013-100UG","price":370.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53037522321773,"sku":"JN009013-1MG","price":1858.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/JN009013-SDS-PAGE-1.jpg?v=1771745898","url":"https:\/\/www.ebiohippo.com\/products\/anti-mycobacterium-tuberculosis-esxa-esat-6-antibody-saa2172-bha21405362","provider":"BioHippo","version":"1.0","type":"link"}