{"product_id":"anti-nup50-rabbit-monoclonal-antibody-bha21010406","title":"Anti-NUP50 Rabbit Monoclonal Antibody","description":"\u003cp\u003eBoster Bio Anti-NUP50 Rabbit Monoclonal Antibody catalog # M06152. Tested in WB, ICC\/IF applications. This antibody reacts with Human, Mouse, Rat.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eProtein\u003c\/strong\u003e: T-cell surface glycoprotein CD3 zeta chain | \u003cstrong\u003eGene\u003c\/strong\u003e: Set1\/Ash2 histone methyltransferase complex subunit ASH2 | \u003cstrong\u003eTarget\u003c\/strong\u003e: NUP50 | \u003cstrong\u003eFunction\u003c\/strong\u003e: Component of the Set1\/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1\/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis. . | \u003cstrong\u003eResearch areas\u003c\/strong\u003e: Cancer Susceptibility,Chromatin Modifying Enzymes,Chromatin Remodeling,Epigenetics and Nuclear Signaling,Methylation,Proto-Oncogenes,Transcription\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHost\u003c\/strong\u003e: Rabbit | \u003cstrong\u003eClonality\/Clone\u003c\/strong\u003e: Monoclonal \/ Clone: 29N16 | \u003cstrong\u003eIsotype\u003c\/strong\u003e: IgG | \u003cstrong\u003eReactivity\u003c\/strong\u003e: Human,Mouse,Rat | \u003cstrong\u003eImmunogen\u003c\/strong\u003e: A synthesized peptide derived from human NUP50 | \u003cstrong\u003eConcentration\u003c\/strong\u003e: 0.5mg\/ml | \u003cstrong\u003ePurification\u003c\/strong\u003e: Affinity-chromatography\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplications\u003c\/strong\u003e: WB, IF, ICC\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eObserved MW\u003c\/strong\u003e: 55 kDa | \u003cstrong\u003eCalculated MW\u003c\/strong\u003e: 68723 MW\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCellular localization\u003c\/strong\u003e: Nucleus .\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTissue details\u003c\/strong\u003e: Ubiquitously expressed. Predominantly expressed in adult heart and testis and fetal lung and liver, with barely detectable expression in adult lung, liver, kidney, prostate, and peripheral leukocytes. .\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eStatus\u003c\/strong\u003e: Active\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"100 uL\/vial \/ Unconjugated","offer_id":53072126542189,"sku":"M06152","price":370.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/m06152-nup50-primary-antibodies-wb-testing-1.jpg?v=1772695660","url":"https:\/\/www.ebiohippo.com\/products\/anti-nup50-rabbit-monoclonal-antibody-bha21010406","provider":"BioHippo","version":"1.0","type":"link"}