{"product_id":"anti-oaz1-antibody-picoband-bha21011884","title":"Anti-OAZ1 Antibody Picoband®","description":"\u003cp\u003eBoster Bio Anti-OAZ1 Antibody Picoband® catalog # A06486-4. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eScientific background\u003c\/strong\u003e: The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto-regulatory circuit. This gene encodes antizyme 1, the first member of the antizyme family, that has broad tissue distribution, and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradation, as well as inhibiting polyamine uptake. Antizyme 1 mRNA contains two potential in-frame AUGs; and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization. Alternatively spliced transcript variants have also been noted for this gene.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCross reactivity\u003c\/strong\u003e: No cross-reactivity with other proteins\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eProtein\u003c\/strong\u003e: Ornithine decarboxylase antizyme 1 | \u003cstrong\u003eGene\u003c\/strong\u003e: ornithine decarboxylase antizyme 1 | \u003cstrong\u003eTarget\u003c\/strong\u003e: OAZ1\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHost\u003c\/strong\u003e: Rabbit | \u003cstrong\u003eClonality\/Clone\u003c\/strong\u003e: Polyclonal | \u003cstrong\u003eIsotype\u003c\/strong\u003e: Rabbit IgG | \u003cstrong\u003eReactivity\u003c\/strong\u003e: Human | \u003cstrong\u003eImmunogen\u003c\/strong\u003e: A synthetic peptide corresponding to a sequence at the N-terminus of human OAZ1. Human OAZ1 shares 100% amino acid (aa) sequence identity with both mouse and rat OAZ1. | \u003cstrong\u003eConcentration\u003c\/strong\u003e: Adding 0.2 ml of distilled water will yield a concentration of 500 μg\/ml. | \u003cstrong\u003ePurification\u003c\/strong\u003e: Immunogen affinity purified.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplications\u003c\/strong\u003e: WB, IHC, ICC, FC, ELISA\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eObserved MW\u003c\/strong\u003e: 25 kDa | \u003cstrong\u003eCalculated MW\u003c\/strong\u003e: 25 kDa\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eStatus\u003c\/strong\u003e: Active\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"100 ug\/vial \/ Unconjugated","offer_id":53072162947437,"sku":"A06486-4","price":370.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Biotin","offer_id":53072396681581,"sku":"A06486-4-Biotin","price":570.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Cy3","offer_id":53072396714349,"sku":"A06486-4-Cy3","price":570.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Fluoro488","offer_id":53072396747117,"sku":"A06486-4-Fluoro488","price":570.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Fluoro550","offer_id":53072396779885,"sku":"A06486-4-Fluoro550","price":570.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Fluoro594","offer_id":53072396812653,"sku":"A06486-4-Fluoro594","price":570.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ FITC","offer_id":53072396845421,"sku":"A06486-4-FITC","price":570.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ HRP","offer_id":53072396878189,"sku":"A06486-4-HRP","price":570.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ APC","offer_id":53072396910957,"sku":"A06486-4-APC","price":820.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ PE","offer_id":53072396943725,"sku":"A06486-4-PE","price":820.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Fluoro647","offer_id":53072396976493,"sku":"A06486-4-Fluoro647","price":670.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Carrier Free","offer_id":53072397009261,"sku":"A06486-4-carrier-free","price":370.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/a06486-4-oaz1-primary-antibodies-wb-testing-1.jpg?v=1772695762","url":"https:\/\/www.ebiohippo.com\/products\/anti-oaz1-antibody-picoband-bha21011884","provider":"BioHippo","version":"1.0","type":"link"}