{"product_id":"anti-phospho-pbk-topk-thr9-rabbit-monoclonal-antibody-bha21010523","title":"Anti-Phospho-PBK\/TOPK (Thr9) Rabbit Monoclonal Antibody","description":"\u003cp\u003eBoster Bio Anti-Phospho-PBK\/TOPK (Thr9) Rabbit Monoclonal Antibody catalog # P02623. Tested in WB, IHC applications. This antibody reacts with Human.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eGene\u003c\/strong\u003e: Adapter molecule crk | \u003cstrong\u003eTarget\u003c\/strong\u003e: PBK | \u003cstrong\u003eFunction\u003c\/strong\u003e: The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk- II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling. . | \u003cstrong\u003eResearch areas\u003c\/strong\u003e: Adapters,Cancer,Cytoplasmic,Signal Transduction\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHost\u003c\/strong\u003e: Rabbit | \u003cstrong\u003eClonality\/Clone\u003c\/strong\u003e: Monoclonal \/ Clone: 30P33 | \u003cstrong\u003eIsotype\u003c\/strong\u003e: IgG | \u003cstrong\u003eReactivity\u003c\/strong\u003e: Human | \u003cstrong\u003eImmunogen\u003c\/strong\u003e: A synthesized peptide derived from human Phospho-PBK\/TOPK (Thr9) | \u003cstrong\u003eConcentration\u003c\/strong\u003e: 0.5mg\/ml | \u003cstrong\u003ePurification\u003c\/strong\u003e: Affinity-chromatography\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplications\u003c\/strong\u003e: WB, IHC\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eObserved MW\u003c\/strong\u003e: 40 kDa | \u003cstrong\u003eCalculated MW\u003c\/strong\u003e: 33831 MW\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCellular localization\u003c\/strong\u003e: Cytoplasm . Cell membrane . Translocated to the plasma membrane upon cell adhesion. .\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTissue details\u003c\/strong\u003e: Expressed in brain, and to a lesser extent in lung, kidney and testis.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePhospho site(s)\u003c\/strong\u003e: Thr9\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eStatus\u003c\/strong\u003e: Active\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"100 uL\/vial \/ Unconjugated","offer_id":53072130572653,"sku":"P02623","price":370.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/p02623-wb.jpg?v=1772621977","url":"https:\/\/www.ebiohippo.com\/products\/anti-phospho-pbk-topk-thr9-rabbit-monoclonal-antibody-bha21010523","provider":"BioHippo","version":"1.0","type":"link"}