{"product_id":"anti-pin4-rabbit-monoclonal-antibody-bha21010409","title":"Anti-PIN4 Rabbit Monoclonal Antibody","description":"\u003cp\u003eBoster Bio Anti-PIN4 Rabbit Monoclonal Antibody catalog # M05181-1. Tested in WB, IHC, ICC\/IF applications. This antibody reacts with Human, Mouse, Rat.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eProtein\u003c\/strong\u003e: T-cell surface glycoprotein CD3 zeta chain | \u003cstrong\u003eGene\u003c\/strong\u003e: Transcription factor 7-like 1 | \u003cstrong\u003eTarget\u003c\/strong\u003e: PIN4 | \u003cstrong\u003eFunction\u003c\/strong\u003e: Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis (By similarity). Down-regulates NQO1, leading to increased mitomycin c resistance. . | \u003cstrong\u003eResearch areas\u003c\/strong\u003e: Growth Factors\/Hormones,Signal Transduction\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHost\u003c\/strong\u003e: Rabbit | \u003cstrong\u003eClonality\/Clone\u003c\/strong\u003e: Monoclonal \/ Clone: 29P19 | \u003cstrong\u003eIsotype\u003c\/strong\u003e: IgG | \u003cstrong\u003eReactivity\u003c\/strong\u003e: Human,Mouse,Rat | \u003cstrong\u003eImmunogen\u003c\/strong\u003e: A synthesized peptide derived from human PIN4 | \u003cstrong\u003eConcentration\u003c\/strong\u003e: 0.5mg\/ml | \u003cstrong\u003ePurification\u003c\/strong\u003e: Affinity-chromatography\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplications\u003c\/strong\u003e: WB, IHC, IF, ICC\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eObserved MW\u003c\/strong\u003e: 14 kDa | \u003cstrong\u003eCalculated MW\u003c\/strong\u003e: 62631 MW\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCellular localization\u003c\/strong\u003e: Nucleus.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTissue details\u003c\/strong\u003e: Detected in hair follicles and skin keratinocytes, and at lower levels in stomach epithelium. .\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eStatus\u003c\/strong\u003e: Active\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"100 uL\/vial \/ Unconjugated","offer_id":53072126083437,"sku":"M05181-1","price":370.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/m05181-1-pin4-primary-antibodies-wb-testing-1.jpg?v=1772695659","url":"https:\/\/www.ebiohippo.com\/products\/anti-pin4-rabbit-monoclonal-antibody-bha21010409","provider":"BioHippo","version":"1.0","type":"link"}