{"product_id":"anti-rabbit-cacna1c-antibody-l57-23r-bha21407640","title":"Anti-Rabbit CACNA1C Antibody (L57\/23R)","description":"\u003cp\u003e\u003cstrong\u003eOverview\u003c\/strong\u003e\u003cbr\u003e\nAnti-Rabbit CACNA1C Antibody (L57\/23R) targets \u003cstrong\u003eCACNA1C\u003c\/strong\u003e (Voltage-dependent L-type calcium channel subunit alpha-1C). Frequently used across IHC workflows, depending on experimental design and sample type. This antibody is suited for workflows commonly used in Molecular \u0026amp; Cellular Biology research.\u003c\/p\u003e\n\n\u003ch3\u003eTarget biology\u003c\/h3\u003e\n\u003cp\u003eCACNA1C (Voltage-dependent L-type calcium channel subunit alpha-1C) encodes an ion channel that mediates Ca²⁺ flux across membranes, influencing excitability and cellular signaling. Channel gating and localization may be modulated by interacting partners and post-translational modifications. Based on the annotated name\/class, the target is most often associated with plasma membrane and\/or intracellular membranes localization, though this can vary by model system.\u003c\/p\u003e\n\n\u003ch3\u003eHow this antibody helps\u003c\/h3\u003e\n\u003cp\u003eAs a monoclonal reagent, this antibody is designed for clone-to-clone consistency and epitope-focused recognition. For best performance, interpret signal in the context of appropriate biological controls and orthogonal readouts when available.\u003c\/p\u003e\n\n\u003ch3\u003eRecommended experimental notes\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eTitrate the antibody to optimize signal-to-noise for your specific sample type and detection system.\u003c\/li\u003e\n\u003cli\u003eUse appropriate positive and negative controls (e.g., target-high vs target-low samples, KO\/KD where available).\u003c\/li\u003e\n\u003cli\u003eFor IHC, optimize fixation and antigen retrieval (buffer\/pH\/heat) and include an isotype\/secondary-only control to assess background.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eAdditional notes\u003c\/h3\u003e\u003cp\u003eFor research use only.\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eFor research use only. Not for diagnostic procedures.\u003c\/em\u003e\u003c\/p\u003e","brand":"Biohippo Inc","offers":[{"title":"50 ug","offer_id":53037001769325,"sku":"TC588013-50UG","price":191.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53037677412717,"sku":"TC588013-100UG","price":370.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53037677445485,"sku":"TC588013-1MG","price":1858.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/TC588013-SDS-PAGE-1.jpg?v=1771747424","url":"https:\/\/www.ebiohippo.com\/products\/anti-rabbit-cacna1c-antibody-l57-23r-bha21407640","provider":"BioHippo","version":"1.0","type":"link"}