{"product_id":"anti-rad51d-rabbit-monoclonal-antibody-bha21010315","title":"Anti-Rad51D Rabbit Monoclonal Antibody","description":"\u003cp\u003eBoster Bio Anti-Rad51D Rabbit Monoclonal Antibody catalog # M02893. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eProtein\u003c\/strong\u003e: T-cell surface glycoprotein CD3 zeta chain | \u003cstrong\u003eGene\u003c\/strong\u003e: Cysteine protease ATG4B | \u003cstrong\u003eTarget\u003c\/strong\u003e: RAD51D | \u003cstrong\u003eFunction\u003c\/strong\u003e: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C- terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. . | \u003cstrong\u003eResearch areas\u003c\/strong\u003e: Cancer,Cardiovascular,Cell Biology,Cell Death,Extracellular Matrix,Invasion\/Microenvironment,Metabolism,Metabolism Processes,Pathways and Processes,Proteolysis\/Ubiquitin,Proteolytic Enzymes,Signal Transduction\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHost\u003c\/strong\u003e: Rabbit | \u003cstrong\u003eClonality\/Clone\u003c\/strong\u003e: Monoclonal \/ Clone: 28R25 | \u003cstrong\u003eIsotype\u003c\/strong\u003e: IgG | \u003cstrong\u003eReactivity\u003c\/strong\u003e: Human,Mouse,Rat | \u003cstrong\u003eImmunogen\u003c\/strong\u003e: A synthesized peptide derived from human Rad51D | \u003cstrong\u003eConcentration\u003c\/strong\u003e: 0.5mg\/ml | \u003cstrong\u003ePurification\u003c\/strong\u003e: Affinity-chromatography\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplications\u003c\/strong\u003e: WB, IHC, IP\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eObserved MW\u003c\/strong\u003e: 35 kDa | \u003cstrong\u003eCalculated MW\u003c\/strong\u003e: 44294 MW\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCellular localization\u003c\/strong\u003e: Cytoplasm .\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTissue details\u003c\/strong\u003e: Mainly expressed in the skeletal muscle, followed by brain, heart, liver and pancreas. .\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eStatus\u003c\/strong\u003e: Active\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"100 uL\/vial \/ Unconjugated","offer_id":53072122806637,"sku":"M02893","price":370.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/m02893-wb.jpg?v=1772621947","url":"https:\/\/www.ebiohippo.com\/products\/anti-rad51d-rabbit-monoclonal-antibody-bha21010315","provider":"BioHippo","version":"1.0","type":"link"}