{"product_id":"anti-spink5-lekti-rabbit-monoclonal-antibody-bha21010404","title":"Anti-SPINK5 \/ LEKTI Rabbit Monoclonal Antibody","description":"\u003cp\u003eBoster Bio Anti-SPINK5 \/ LEKTI Rabbit Monoclonal Antibody catalog # M03254. Tested in WB application. This antibody reacts with Human, Mouse, Rat.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eProtein\u003c\/strong\u003e: T-cell surface glycoprotein CD3 zeta chain | \u003cstrong\u003eGene\u003c\/strong\u003e: Calcium\/calmodulin-dependent protein kinase type II subunit alpha | \u003cstrong\u003eTarget\u003c\/strong\u003e: SPINK5 | \u003cstrong\u003eFunction\u003c\/strong\u003e: CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity). Phosphorylates transcription factor FOXO3 on 'Ser-298' (PubMed:23805378). Activates FOXO3 transcriptional activity (By similarity). . | \u003cstrong\u003eResearch areas\u003c\/strong\u003e: Calcium Signaling,Calmodulin Pathway,Cardiovascular,Hypertrophy,Neuroscience,Neurotransmission,Protein Phosphorylation,Ser\/Thr Kinases,Signal Transduction,Signaling Pathway\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHost\u003c\/strong\u003e: Rabbit | \u003cstrong\u003eClonality\/Clone\u003c\/strong\u003e: Monoclonal \/ Clone: 29S14 | \u003cstrong\u003eIsotype\u003c\/strong\u003e: IgG | \u003cstrong\u003eReactivity\u003c\/strong\u003e: Human,Mouse,Rat | \u003cstrong\u003eImmunogen\u003c\/strong\u003e: A synthesized peptide derived from human SPINK5 \/ LEKTI | \u003cstrong\u003eConcentration\u003c\/strong\u003e: 0.5mg\/ml | \u003cstrong\u003ePurification\u003c\/strong\u003e: Affinity-chromatography\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplications\u003c\/strong\u003e: WB\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eObserved MW\u003c\/strong\u003e: 121 kDa | \u003cstrong\u003eCalculated MW\u003c\/strong\u003e: 54088 MW\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCellular localization\u003c\/strong\u003e: Cell junction, synapse, presynaptic cell membrane . Cell junction, synapse . Postsynaptic lipid rafts. .\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTissue details\u003c\/strong\u003e: Expressed in brain in the thalamus, in fetal and adult lung and in placenta. .\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eStatus\u003c\/strong\u003e: Active\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"100 uL\/vial \/ Unconjugated","offer_id":53072127918445,"sku":"M03254","price":370.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/m03254-wb.jpg?v=1772621963","url":"https:\/\/www.ebiohippo.com\/products\/anti-spink5-lekti-rabbit-monoclonal-antibody-bha21010404","provider":"BioHippo","version":"1.0","type":"link"}