{"product_id":"anti-thrombomodulin-cd141-rabbit-monoclonal-antibody-bha21010318","title":"Anti-Thrombomodulin \/ CD141 Rabbit Monoclonal Antibody","description":"\u003cp\u003eBoster Bio Anti-Thrombomodulin \/ CD141 Rabbit Monoclonal Antibody catalog # M01325-2. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Mouse, Rat.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eProtein\u003c\/strong\u003e: Glycogen synthase kinase-3 beta (gsk3b) | \u003cstrong\u003eGene\u003c\/strong\u003e: Thrombomodulin | \u003cstrong\u003eTarget\u003c\/strong\u003e: Thbd | \u003cstrong\u003eFunction\u003c\/strong\u003e: Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. | \u003cstrong\u003eResearch areas\u003c\/strong\u003e: Cardiovascular,Stem Cells\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHost\u003c\/strong\u003e: Rabbit | \u003cstrong\u003eClonality\/Clone\u003c\/strong\u003e: Monoclonal \/ Clone: 28T28 | \u003cstrong\u003eIsotype\u003c\/strong\u003e: IgG | \u003cstrong\u003eReactivity\u003c\/strong\u003e: Mouse,Rat | \u003cstrong\u003eImmunogen\u003c\/strong\u003e: A synthesized peptide derived from human Thrombomodulin \/ CD141 | \u003cstrong\u003eConcentration\u003c\/strong\u003e: 0.5mg\/ml | \u003cstrong\u003ePurification\u003c\/strong\u003e: Affinity-chromatography\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplications\u003c\/strong\u003e: WB, IHC, ICC, FC\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eObserved MW\u003c\/strong\u003e: 105 kDa | \u003cstrong\u003eCalculated MW\u003c\/strong\u003e: 60329 MW\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCellular localization\u003c\/strong\u003e: Membrane; Single-pass type I membrane protein.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTissue details\u003c\/strong\u003e: Endothelial cells are unique in synthesizing thrombomodulin.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eStatus\u003c\/strong\u003e: Active\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"100 uL\/vial \/ Unconjugated","offer_id":53072121364845,"sku":"M01325-2","price":370.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/m01325-2-wb.jpg?v=1772621946","url":"https:\/\/www.ebiohippo.com\/products\/anti-thrombomodulin-cd141-rabbit-monoclonal-antibody-bha21010318","provider":"BioHippo","version":"1.0","type":"link"}