{"product_id":"anti-zebrafish-psmc5-antibody-bha21012399","title":"Anti-Zebrafish PSMC5 Antibody","description":"\u003cp\u003eBoster Bio Anti-Zebrafish PSMC5 Antibody catalog # AZQ6AZC1. Tested in IHC applications. This antibody reacts with Zebrafish.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eScientific background\u003c\/strong\u003e: 26S protease regulatory subunit 8, also known as 26S proteasome AAA-ATPase subunit Rpt6, is an enzyme that in humans is encoded by the PSMC5 gene. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP\/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTarget\u003c\/strong\u003e: PSMC5\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHost\u003c\/strong\u003e: Rabbit | \u003cstrong\u003eClonality\/Clone\u003c\/strong\u003e: Polyclonal | \u003cstrong\u003eIsotype\u003c\/strong\u003e: Rabbit IgG | \u003cstrong\u003eReactivity\u003c\/strong\u003e: Zebrafish | \u003cstrong\u003eImmunogen\u003c\/strong\u003e: E.coli-derived zebrafish PSMC5 recombinant protein (Position: N41-K393). | \u003cstrong\u003eConcentration\u003c\/strong\u003e: Adding 0.2 ml of distilled water will yield a concentration of 500 μg\/ml. | \u003cstrong\u003ePurification\u003c\/strong\u003e: Immunogen affinity purified.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplications\u003c\/strong\u003e: IHC\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eStatus\u003c\/strong\u003e: Active\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"100 ug\/vial \/ Unconjugated","offer_id":53072180511085,"sku":"AZQ6AZC1","price":470.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Biotin","offer_id":53072580739437,"sku":"AZQ6AZC1-Biotin","price":670.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Cy3","offer_id":53072580772205,"sku":"AZQ6AZC1-Cy3","price":670.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Fluoro488","offer_id":53072580804973,"sku":"AZQ6AZC1-Fluoro488","price":670.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Fluoro550","offer_id":53072580837741,"sku":"AZQ6AZC1-Fluoro550","price":670.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Fluoro594","offer_id":53072580870509,"sku":"AZQ6AZC1-Fluoro594","price":670.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ FITC","offer_id":53072580903277,"sku":"AZQ6AZC1-FITC","price":670.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ HRP","offer_id":53072580936045,"sku":"AZQ6AZC1-HRP","price":670.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ APC","offer_id":53072580968813,"sku":"AZQ6AZC1-APC","price":920.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ PE","offer_id":53072581001581,"sku":"AZQ6AZC1-PE","price":920.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Fluoro647","offer_id":53072581034349,"sku":"AZQ6AZC1-Fluoro647","price":770.0,"currency_code":"USD","in_stock":true},{"title":"100 ug\/vial \/ Carrier Free","offer_id":53072581067117,"sku":"AZQ6AZC1-carrier-free","price":470.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/azq6azc1-psmc5-primary-antibodies-ihc-testing-1.jpg?v=1772695830","url":"https:\/\/www.ebiohippo.com\/products\/anti-zebrafish-psmc5-antibody-bha21012399","provider":"BioHippo","version":"1.0","type":"link"}