{"product_id":"asph-human-bhz11000685","title":"ASPH Human","description":"\u003cdiv class=\"bhp-desc\"\u003e\n\u003ch3 style=\"color:#1a5c58;margin:12px 0 4px\"\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eAspartate Beta-Hydroxylase Human Recombinant\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"bhp-desc\"\u003e\n\u003ch3 style=\"color:#1a5c58;margin:12px 0 4px\"\u003eOverview\u003c\/h3\u003e\n\u003cp\u003eASPH hydroxylates an Asp or Asn residue in EGF domains. ASPH is involved in calcium homeostasis. ASPH is expressed from two promoters and goes through extensive alternative splicing. The encoded set of ASPH proteins share varying quantities of overlap near their N-termini although have considerable differences in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl\/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the EGF domain, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Further isoforms diverge mainly in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and  sarcoplasmic reticulum.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"bhp-desc\"\u003e\n\u003ch3 style=\"color:#1a5c58;margin:12px 0 4px\"\u003eSpecifications\u003c\/h3\u003e\n\u003ctable style=\"width:100%;border-collapse:collapse;font-size:0.92em\"\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align:left;padding:4px 8px;background:#e8f4f3;width:180px;font-weight:bold\"\u003ePurity\u003c\/th\u003e\n\u003ctd style=\"padding:4px 8px\"\u003eGreater than 90.0% as determined by SDS-PAGE.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align:left;padding:4px 8px;background:#e8f4f3;width:180px;font-weight:bold\"\u003eFormulation\u003c\/th\u003e\n\u003ctd style=\"padding:4px 8px\"\u003eThe ASPH protein solution contains 20mM Tris-HCl pH-8, 1mM DTT and 10% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align:left;padding:4px 8px;background:#e8f4f3;width:180px;font-weight:bold\"\u003eStorage\u003c\/th\u003e\n\u003ctd style=\"padding:4px 8px\"\u003eStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align:left;padding:4px 8px;background:#e8f4f3;width:180px;font-weight:bold\"\u003eExpression System\u003c\/th\u003e\n\u003ctd style=\"padding:4px 8px\"\u003eEscherichia Coli.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5µg","offer_id":53340117533037,"sku":"ENZ-488-5µg","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":53340169273709,"sku":"ENZ-488-20µg","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":53340169306477,"sku":"ENZ-488-1mg","price":3600.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-asph-human-ENZ-488.png?v=1782158460","url":"https:\/\/www.ebiohippo.com\/products\/asph-human-bhz11000685","provider":"BioHippo","version":"1.0","type":"link"}