{"product_id":"atp4b-antibody-potassium-transporting-atpase-subunit-beta-bha17135168","title":"ATP4B Antibody \/ Potassium-transporting ATPase subunit beta","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\u003cp\u003eATP4B Antibody \/ Potassium-transporting ATPase subunit beta is an antibody targeting \u003cstrong\u003eATP4B\u003c\/strong\u003e. Host: \u003cstrong\u003eRabbit\u003c\/strong\u003e. Polyclonal. Format: Lyophilized. Applications: ELISA, FACS, IF, IHC, WB.\u003c\/p\u003e\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTarget:\u003c\/strong\u003e ATP4B.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmunogen:\u003c\/strong\u003e E.coli-derived human ATP4B recombinant protein (Position: Y60-D277) was used as the immunogen for the ATP4B antibody..\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpecies reactivity:\u003c\/strong\u003e Human, Mouse, Rat.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConjugate:\u003c\/strong\u003e Unconjugated (no label listed).\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eBiological background (from provided description)\u003c\/h2\u003e\u003cp\u003eATP4B antibody detects Gastric H+\/K+ ATPase subunit beta, encoded by the ATP4B gene on chromosome 13q34. ATP4B antibody is widely used in gastrointestinal biology, acid secretion research, and studies of gastric disorders. ATP4B encodes the beta subunit of the gastric proton pump, a P-type ATPase that exchanges intracellular H+ for extracellular K+, enabling secretion of gastric acid into the stomach lumen.\u003c\/p\u003e\u003ch2\u003eCommon research applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eWB:\u003c\/strong\u003e relative abundance and band pattern assessment using appropriate controls.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIHC:\u003c\/strong\u003e tissue distribution assessment; interpret with matched controls.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIF\/ICC:\u003c\/strong\u003e subcellular localization imaging with proper background controls.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eAccount for isoforms, paralogs, and post-translational modifications when interpreting signal.\u003c\/li\u003e\n\u003cli\u003eSupport specificity with biological controls (e.g., KO\/KD where available) and technical controls (e.g., secondary-only\/isotype).\u003c\/li\u003e\n\u003c\/ul\u003e\u003c!-- Sources (internal): - UniProt Knowledgebase (UniProt) – https:\/\/www.uniprot.org\/ - NCBI Gene (NIH\/NLM) – https:\/\/www.ncbi.nlm.nih.gov\/gene\/ - ZFIN – https:\/\/zfin.org\/ - Ensembl – https:\/\/www.ensembl.org\/ - Nature Methods (2015): A proposal for validation of antibodies – https:\/\/www.nature.com\/articles\/nmeth.3230 --\u003e","brand":"NSJ Bioreagents","offers":[{"title":"Adding 0.2 ml of distilled water will yield a concentration of 500 ug\/ml \/ 100 ug","offer_id":53046721118573,"sku":"FY12265","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/get_image_2a92ee1e-8d30-46f0-a6e2-b8e7416762a0.jpg?v=1782236988","url":"https:\/\/www.ebiohippo.com\/products\/atp4b-antibody-potassium-transporting-atpase-subunit-beta-bha17135168","provider":"BioHippo","version":"1.0","type":"link"}