{"product_id":"b-cpap-cell-bhc11101200","title":"B-CPAP cell","description":"B-CPAP is a human papillary thyroid carcinoma cell line that was established from the primary tumor of a 74-year-old woman. The cell line exhibits epithelial-like morphology and is commonly used in research to study thyroid cancer biology, including mechanisms of tumorigenesis and metastasis. B-CPAP cells are notable for harboring a BRAF V600E mutation, which is a common genetic alteration associated with aggressive thyroid cancers and serves as a critical model for evaluating BRAF inhibitors as therapeutic agents.\n\nIn addition to the BRAF mutation, B-CPAP cells express thyroid-specific markers such as thyroglobulin and thyroid-stimulating hormone receptor, making them a valuable model for studying thyroid gland function and pathology. They have been extensively used in studies investigating the signaling pathways involved in thyroid cancer progression, including MAPK\/ERK pathway activation. These cells are also employed in drug resistance and apoptosis studies, providing insights into the mechanisms that might underpin therapeutic failures in thyroid cancer treatments.\n\u003cp style=\"display:none\"\u003eSKU:BHC11101200\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950198026605,"sku":"305081","price":395.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/B-CPAP_20P4_2010x01_20040923_ch00_1920x1920_78a77fc0-6747-4857-9a9b-75e09bf7d3aa.jpg?v=1769068954","url":"https:\/\/www.ebiohippo.com\/products\/b-cpap-cell-bhc11101200","provider":"BioHippo","version":"1.0","type":"link"}