{"product_id":"benzoyl-coenzyme-a-lithium-salt-bhb21200054","title":"Benzoyl Coenzyme A, Lithium salt","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\n\u003cp\u003eBenzoyl Coenzyme A, Lithium salt is a biochemical supplied by Coenza for use in enzymology and metabolic research. Available as Lyophilized powder, purity ≥ 95%, suitable for in vitro assays and pathway studies.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eAlso known as:\u003c\/em\u003e Benzoyl-CoA lithium salt.\u003c\/p\u003e\n\u003ch2\u003eKey Elements and Design Rationale\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormula \/ MW \/ Purity:\u003c\/strong\u003e C28H37N7O17P3S · xLi; 871.64 g\/mol (free acid basis); ≥ 95%. The Lithium salt form provides enhanced aqueous stability.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm \/ Solubility:\u003c\/strong\u003e Lyophilized powder; Soluble in water.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSynonyms:\u003c\/strong\u003e Benzoyl-CoA lithium salt.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrigin:\u003c\/strong\u003e Biosynthetic synthesis.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eBiological Background\u003c\/h2\u003e\n\u003cp\u003eBenzoyl coenzyme A (Benzoyl-CoA) is an intermediate in the CoA-dependent epoxide pathway, synthesized from benzoate and further converted into 2,3-epoxybenzoyl-CoA by enzymes like benzoyl-CoA reductase and oxygenase. It serves as a substrate for type-III polyketide synthase, plant enzymes like biphenyl synthase and benzophenone synthase, and is involved in the gentisate pathway of Comamonas testosteroni. Benzoyl CoA is also used in studies of benzoate metabolism, alcohol acyltransferases, and the synthesis of polyketide derivatives such as biphenyl and dibenzofuran (Bastard et al., 2011; Hirayama et al., 2018).\u003c\/p\u003e\n\u003ch2\u003eResearch Relevance and Current Trends\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAcyl-CoA metabolism increasingly linked to histone acylation marks and epigenetic regulation in cancer and metabolic disease research.\u003c\/li\u003e\n\u003cli\u003eGrowing interest in short-chain fatty acid CoA thioesters as mediators of gut microbiome–host metabolic crosstalk.\u003c\/li\u003e\n\u003cli\u003eCoA-dependent enzymes investigated as drug targets in infectious disease and neurometabolic disorder research.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eCommon Research Applications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eEnzyme kinetics assays — direct substrate for acyltransferases, thiolases, and dehydrogenases.\u003c\/li\u003e\n\u003cli\u003eMetabolic flux analysis — isotope-labeled variants available for stable-isotope tracing.\u003c\/li\u003e\n\u003cli\u003eIn vitro pathway reconstitution for fatty acid β-oxidation, TCA cycle, or polyketide biosynthesis.\u003c\/li\u003e\n\u003cli\u003eBiochemical characterization of CoA-binding proteins by activity assays or binding measurements.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eNotes for Experimental Interpretation\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eCoA thioesters hydrolyze at neutral–alkaline pH; prepare working solutions fresh and keep on ice.\u003c\/li\u003e\n\u003cli\u003eDifferent salt forms share the same core structure — normalize concentrations using the free-acid MW when comparing across forms.\u003c\/li\u003e\n\u003cli\u003eThiol oxidation may occur upon air exposure; use under inert atmosphere or with reducing agents where appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Coenza","offers":[{"title":"10 mg","offer_id":53249727922541,"sku":"A-54-10MG","price":488.7,"currency_code":"USD","in_stock":true},{"title":"25 mg","offer_id":53249732378989,"sku":"A-54-25MG","price":846.6,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/53dbfa_7aea1fb25ffd48928240e285514c7ed8_mv2.png?v=1776855585","url":"https:\/\/www.ebiohippo.com\/products\/benzoyl-coenzyme-a-lithium-salt-bhb21200054","provider":"BioHippo","version":"1.0","type":"link"}