{"product_id":"bovine-milk-lactoglobulin-bhp10506079","title":"Bovine milk β-Lactoglobulin","description":"\u003ch2\u003eOverview\u003c\/h2\u003e \u003cp\u003eNative bovine β-lactoglobulin (Beta-LG) is purified from Bovine milk and supplied as a research reagent. It is commonly used as a reference material in biochemical and analytical workflows, and to support interpretation when naturally occurring proteoforms (for example, glycosylation or other post‑translational modifications) may matter.\u003c\/p\u003e \u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e \u003cul\u003e \u003cli\u003e\n\u003cstrong\u003eNative-source preparation:\u003c\/strong\u003e Purified from a biological source, which can be useful when studying naturally occurring proteoforms and complex formation.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eMolecular form:\u003c\/strong\u003e Full length protein.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eClassification:\u003c\/strong\u003e Storage Protein\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e \u0026gt;95%(SDS-PAGE) (as reported).\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Liquid\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eCommon names \/ aliases:\u003c\/strong\u003e Beta-LG\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eThese elements help determine how the reagent behaves in binding, stability, or quantitative measurements, and how closely it reflects biology in the chosen model system.\u003c\/p\u003e \u003ch2\u003eBiological background\u003c\/h2\u003e \u003cp\u003eβ-Lactoglobulin is a major whey protein in bovine milk and a member of the lipocalin family, capable of binding hydrophobic ligands. It is a widely studied model for food protein structure, allergenicity, and ligand-binding behavior.\u003c\/p\u003e\u003cp\u003eβ-Lactoglobulin is the major whey protein of cow and sheep's milk (~3 g\/l), and is also present in many other mammalian species; a notable exception being humans. Bovine β-lactoglobulin is a relatively small protein of 162 residues, with an 18.4 kDa molecular weight.In physiological conditions it is predominantly dimeric, but dissociates to a monomer below about pH 3.\u003c\/p\u003e \u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e \u003cul\u003e \u003cli\u003eFood allergy and epitope mapping studies evaluating how processing affects β-lactoglobulin structure and immune recognition.\u003c\/li\u003e \u003cli\u003eProtein–ligand interaction research (fatty acids, vitamins, small molecules) leveraging lipocalin binding pockets.\u003c\/li\u003e \u003cli\u003eFormulation and delivery concepts using milk proteins as carriers in food and biomaterials research.\u003c\/li\u003e \u003c\/ul\u003e \u003ch2\u003eCommon research applications\u003c\/h2\u003e \u003cul\u003e \u003cli\u003eReference material for allergen-related assays and food protein analytics.\u003c\/li\u003e \u003cli\u003eModel protein for studying ligand binding, unfolding\/refolding, and stability.\u003c\/li\u003e \u003cli\u003eBenchmark in chromatographic and electrophoretic method development.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eUse changes in abundance, binding, or activity readouts as context-dependent signals. In many systems, differences may reflect regulation, compartment shifts, complex formation, or sample-matrix effects rather than a single direct mechanism.\u003c\/p\u003e \u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e \u003cul\u003e \u003cli\u003eβ-Lactoglobulin can undergo conformational changes with pH\/temperature; interpret binding and immunoreactivity with context.\u003c\/li\u003e \u003cli\u003eLigand occupancy can shift apparent stability; document sample history for comparability.\u003c\/li\u003e \u003cli\u003eAllergen assays are sensitive to trace contaminants; use appropriate controls and standards.\u003c\/li\u003e \u003c\/ul\u003e \u003c!-- Sources (internal): - UniProt: https:\/\/www.uniprot.org\/uniprotkb?query=beta-lactoglobulin Beta-LG - NCBI Gene: https:\/\/www.ncbi.nlm.nih.gov\/gene\/?term=beta-lactoglobulin Beta-LG - PubMed: https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=beta-lactoglobulin Beta-LG%20review --\u003e","brand":"CUSABIO TECHNOLOGY LLC","offers":[{"title":"10 mg","offer_id":53052977774957,"sku":"CSB-NP002801B-10MG","price":1600.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53052977807725,"sku":"CSB-NP002801B-1MG","price":200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/CSB-NP002801B-SDS.jpg?v=1772166487","url":"https:\/\/www.ebiohippo.com\/products\/bovine-milk-lactoglobulin-bhp10506079","provider":"BioHippo","version":"1.0","type":"link"}