{"product_id":"c-646-bhb11900138","title":"C-646","description":"\u003cp\u003eC-646 is a potent and selective inhibitor of the histone acetyltransferase p300\/CBP, with a Ki of 400 nM. In neuroscience, C-646 has been shown to enhance synaptic plasticity and memory formation, particularly in fear extinction paradigms. It also promotes tau deacetylation, thereby reducing levels of pathogenic phosphorylated tau (p-tau), a hallmark of Alzheimer’s disease. These properties position C-646 as a promising epigenetic modulator for neurodegenerative disease research, offering insights into chromatin remodeling and transcriptional regulation in neuronal health and disease.\u003c\/p\u003e","brand":"StressMarq Biosciences Inc.","offers":[{"title":"5 mg","offer_id":53040945594733,"sku":"SIH-350-5MG","price":115.0,"currency_code":"USD","in_stock":true},{"title":"25 mg","offer_id":53040963486061,"sku":"SIH-350-25MG","price":496.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/SIH-350_C-646_Chemical_Structure.png?v=1771837630","url":"https:\/\/www.ebiohippo.com\/products\/c-646-bhb11900138","provider":"BioHippo","version":"1.0","type":"link"}