{"product_id":"ca-ix-monoclonal-antibody-bha12101619","title":"CA IX Monoclonal Antibody","description":"\u003cstyle\u003e\n.bhp-desc{font-size:16px;color:#1a1a1a;line-height:1.7}\n.bhp-desc h2{font-size:18px;font-weight:700;color:#003366;margin:24px 0 10px;padding-bottom:6px;border-bottom:2px solid #003366}\n.bhp-desc p{margin:0 0 12px}\n.bhp-desc .bhp-spec-table{width:100%;border-collapse:collapse;margin:12px 0 18px}\n.bhp-desc .bhp-spec-table th{width:36%;text-align:left;padding:8px 12px;background:#e8f0fb;color:#003366;font-weight:600;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-spec-table td{padding:8px 12px;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-qc-badge{display:inline-block;background:#e6f4ea;color:#1a7a3c;border:1px solid #a8d5b5;border-radius:4px;padding:6px 14px;font-size:14px;font-weight:600}\n.bhp-desc .bhp-warning-box{background:#fff8e6;border-left:4px solid #e6a817;padding:10px 14px;margin:10px 0 14px;border-radius:0 4px 4px 0}\n.bhp-desc .bhp-cat-pill{display:inline-block;background:#003366;color:#fff;border-radius:20px;padding:3px 12px;font-size:13px;margin-bottom:10px}\n\u003c\/style\u003e\n\u003cdiv class=\"bhp-desc\"\u003e\n\u003ch2\u003eProduct Overview\u003c\/h2\u003e\n\u003cspan class=\"bhp-cat-pill\"\u003ePrimary Antibody\u003c\/span\u003e\n\u003cp\u003eThis antibody targets CA9 and detects endogenous levels of CA9 protein.\u003c\/p\u003e\n\n\u003ch2\u003eValidated Applications\u003c\/h2\u003e\n\u003ctable class=\"bhp-spec-table\"\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eApplication\u003c\/th\u003e\n\u003cth\u003eDilution Guidance\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eWestern Blot (WB)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eRefer to datasheet for recommended working dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eImmunohistochemistry (IHC)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eRefer to datasheet for recommended working dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eImmunofluorescence (IF)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eRefer to datasheet for recommended working dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFlow Cytometry (FC)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eRefer to datasheet for recommended working dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eELISA\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eRefer to datasheet for recommended working dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cspan class=\"bhp-qc-badge\"\u003e✔ Validated by Bioassay Technology Laboratory\u003c\/span\u003e\n\n\u003ch2\u003eAntibody Specifications\u003c\/h2\u003e\n\u003ctable class=\"bhp-spec-table\"\u003e\n\u003ctr\u003e\n\u003cth\u003eTarget\u003c\/th\u003e\n\u003ctd\u003eCA9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eHost\u003c\/th\u003e\n\u003ctd\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eClonality\u003c\/th\u003e\n\u003ctd\u003eMonoclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eIsotype\u003c\/th\u003e\n\u003ctd\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eReactivity\u003c\/th\u003e\n\u003ctd\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003ePurification\u003c\/th\u003e\n\u003ctd\u003eAffinity Purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eConcentration\u003c\/th\u003e\n\u003ctd\u003e1 mg\/ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eImmunogen\u003c\/th\u003e\n\u003ctd\u003ePurified recombinant fragment of human CA IX expressed in E. Coli.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eFormulation\u003c\/th\u003e\n\u003ctd\u003eAscitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eStorage\u003c\/th\u003e\n\u003ctd\u003e-20°C for 1 year\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eGene ID\u003c\/th\u003e\n\u003ctd\u003eHuman: 768\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eUniProt\u003c\/th\u003e\n\u003ctd\u003e\n\u003ca href=\"https:\/\/www.uniprot.org\/uniprotkb\/Q16790\" target=\"_blank\" style=\"color:#003366\"\u003eQ16790\u003c\/a\u003e (Human: Q16790; Mouse: Q8VHB5)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\n\u003ch2\u003eScientific Background\u003c\/h2\u003e\n\u003cp\u003e\u003c\/p\u003e\n\u003cp\u003eCarbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.\u003c\/p\u003e\n\u003ch2\u003eAlternative Names\u003c\/h2\u003e\n\u003cp style=\"color:#555\"\u003eCA9; G250; MN; Carbonic anhydrase 9; Carbonate dehydratase IX; Carbonic anhydrase IX; CA-IX; CAIX; Membrane antigen MN; P54; 58N; Renal cell carcinoma-associated antigen G250; RCC-associated antigen G250; pMW1\u003c\/p\u003e\n\n\u003ch2\u003eSafety \u0026amp; Handling\u003c\/h2\u003e\n\u003cdiv class=\"bhp-warning-box\"\u003e\n\u003cstrong\u003e⚠ Research Use Only (RUO).\u003c\/strong\u003e Not approved for diagnostic or therapeutic use. Handle with standard laboratory safety precautions. Contains sodium azide — avoid contact with skin\/eyes; dispose per local regulations.\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Bioassay Technology Laboratory","offers":[{"title":"50 uL","offer_id":53327964864877,"sku":"BT-MCA0248-50UL","price":180.0,"currency_code":"USD","in_stock":true},{"title":"100 uL","offer_id":53327975285101,"sku":"BT-MCA0248-100UL","price":300.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BT-MCA0248_20Western_20Blot_201.jpg?v=1778728712","url":"https:\/\/www.ebiohippo.com\/products\/ca-ix-monoclonal-antibody-bha12101619","provider":"BioHippo","version":"1.0","type":"link"}