{"product_id":"capan-1-cell-bhc11100185","title":"Capan-1 cell","description":"The Capan-1 cell line is derived from a human pancreatic adenocarcinoma and was established from the ascitic fluid of a 40-year-old Caucasian male. It was first characterized in 1975 and is particularly noted for its ductal epithelial morphology, which closely resembles that of primary pancreatic tumors. Capan-1 cells are extensively used in research aimed at understanding pancreatic cancer biology, including studies on tumor progression, metastasis, and treatment resistance. This cell line is well-regarded for its ability to produce mucin, a characteristic feature of many pancreatic adenocarcinomas, thus serving as a model for mucinous pancreatic cancer.\n\nGenetically, Capan-1 harbors mutations in the KRAS gene, which are typical of pancreatic cancer, as well as alterations in other cancer-related genes such as TP53 and SMAD4. These mutations make the Capan-1 cell line a valuable tool for studying the molecular mechanisms underlying pancreatic cancer and for the preclinical evaluation of new therapeutic agents targeting these pathways. Furthermore, Capan-1 cells are used to study the biology of pancreatic cancer stem cells, offering insights into the behaviors that drive cancer recurrence and resistance to conventional therapies.\n\u003cp style=\"display:none\"\u003eSKU:BHC11100185\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950200582509,"sku":"300143","price":395.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/capan-1-_281_29_1920x1920_df02430a-19f1-418a-bb8f-cfe22fd105d5.jpg?v=1769068984","url":"https:\/\/www.ebiohippo.com\/products\/capan-1-cell-bhc11100185","provider":"BioHippo","version":"1.0","type":"link"}