{"product_id":"cebpg-antibody-ccaat-enhancer-binding-protein-gamma-bha17135580","title":"CEBPG Antibody \/ CCAAT\/enhancer-binding protein gamma","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\u003cp\u003eCEBPG Antibody \/ CCAAT\/enhancer-binding protein gamma is a anti-CEBPG Rabbit antibody Polyclonal (rabbit origin) supplied in Lyophilized format. Recommended for workflows such as Western blot (WB), Flow cytometry (FACS), ELISA with listed reactivity in Human, Mouse, Rat.\u003c\/p\u003e\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTarget:\u003c\/strong\u003e CEBPG\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntibody details:\u003c\/strong\u003e Rabbit, Polyclonal (rabbit origin), isotype Rabbit IgG\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Lyophilized\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eApplications (as listed):\u003c\/strong\u003e WB, FACS, ELISA\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eBiological background\u003c\/h2\u003e\u003cdiv\u003eCEBPG antibody targets CCAAT\/enhancer-binding protein gamma, a member of the CEBP family of transcription factors that regulate genes involved in immune response, metabolism, and cell differentiation. CEBPG lacks a canonical transactivation domain and instead acts as a dimerization partner for other CEBP family members such as CEBPA, CEBPB, and CEBPD, influencing transcription through heterodimer formation. This modulatory activity enables CEBPG to fine-tune expression of genes associated with inflammation, DNA repair, and oxidative stress responses. The protein is localized primarily in the nucleus, where it binds to CCAAT motifs within promoter regions and modulates transcriptional outcomes depending on its dimerization partner.\u003cbr\u003e\u003cbr\u003eCEBPG is encoded by the CEBPG gene located on chromosome 19q13.11 and produces a protein of approximately 15 kilodaltons. It is ubiquitously expressed but particularly abundant in immune cells, liver, and lung tissues. Through interaction with CEBPB, CEBPG contributes to the regulation of cytokine expression, lipid metabolism, and acute phase responses. In addition to its transcriptional role, CEBPG has been linked to DNA damage tolerance pathways, where it may cooperate with ATF4 to activate antioxidant genes during cellular stress. The CEBPG antibody is therefore widely used in studies of transcriptional regulation, inflammation, and stress response signaling.\u003cbr\u003e\u003cbr\u003eResearch indicates that CEBPG participates in regulatory networks controlling macrophage activation and epithelial defense responses. Overexpression or silencing of CEBPG affects the expression of downstream effectors such as SOD2, GPX1, and TNF, linking this factor to redox balance and inflammatory signaling. Because of its cooperative interactions with other CEBP proteins, CEBPG serves as an important hub in transcriptional cascades influencing differentiation and immune adaptation. The CEBPG antibody is validated for western blotting, immunofluorescence, and chromatin immunoprecipitation assays, enabling analysis of protein expression and DNA-binding activity.\u003c\/div\u003e\u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eConnecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).\u003c\/li\u003e\n\u003cli\u003eConsidering isoforms and post-translational regulation when interpreting protein-level changes.\u003c\/li\u003e\n\u003cli\u003eComparing results across species and model systems with matched controls.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eCommon research applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eWestern blotting:\u003c\/strong\u003e compare relative abundance and activation-state changes across conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFlow cytometry:\u003c\/strong\u003e quantify target-positive populations and signal shifts at single-cell resolution.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eELISA:\u003c\/strong\u003e support antibody-based quantification in assay formats where applicable.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eInterpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.\u003c\/p\u003e\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eSignal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.\u003c\/li\u003e\n\u003cli\u003eSpecies differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eAntibody notes:\u003c\/strong\u003e Polyclonal antibodies recognize multiple epitopes, which can broaden the epitope footprint and may increase sensitivity in some contexts.\u003c\/p\u003e\u003c!-- Sources (internal): - UniProt search — UniProt — https:\/\/www.uniprot.org\/uniprotkb?query=CEBPG - NCBI Gene search — NCBI — https:\/\/www.ncbi.nlm.nih.gov\/gene\/?term=CEBPG - Ensembl search — Ensembl — https:\/\/www.ensembl.org\/Multi\/Search\/Results?q=CEBPG - Human Protein Atlas search — HPA — https:\/\/www.proteinatlas.org\/search\/CEBPG - PubMed (review) — NLM — https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=CEBPG+review --\u003e","brand":"NSJ Bioreagents","offers":[{"title":"Adding 0.2 ml of distilled water will yield a concentration of 500 ug\/ml \/ 100 ug","offer_id":53047296590189,"sku":"FY12677","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/get_image_22c5fc18-b556-4e9a-9d35-d3eb08195c5a.jpg?v=1782237029","url":"https:\/\/www.ebiohippo.com\/products\/cebpg-antibody-ccaat-enhancer-binding-protein-gamma-bha17135580","provider":"BioHippo","version":"1.0","type":"link"}