{"product_id":"cho-b7h3-cell-bhc11101491","title":"CHO-B7H3 cell","description":"Disclaimer: The prices displayed for cell lines are exclusively for not-for-profit customers. If you represent a commercial entity, please contact us for alternative pricing.The CHO-B7H3 cell line is a stable recombinant CHO (Chinese Hamster Ovary) cell line engineered to express the B7-H3 receptor at a high level, approximately 395,000 molecules per cell. This cell line was developed using innovative landing pad technology, which ensures precise and reproducible integration of the B7-H3 gene at a specific, pre-validated genomic locus. B7-H3, also known as CD276, is a member of the B7 family of immune checkpoint proteins and is overexpressed in various cancers. It plays a critical role in immune evasion by tumor cells and is associated with poor prognosis in cancer patients. This makes B7-H3 a promising target for cancer immunotherapy, particularly in the development of checkpoint inhibitors and antibody-drug conjugates.\nThe expression of B7-H3 in this cell line was confirmed using flow cytometry with a target-specific antibody, ensuring reliable and consistent receptor density across the cell population.\n\u003cp style=\"display:none\"\u003eSKU:BHC11101491\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950201237869,"sku":"305417","price":5000.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/cho-hd_1920x1920_5e76e15e-17b7-4b33-b52d-a8b8a6040417.jpg?v=1769068990","url":"https:\/\/www.ebiohippo.com\/products\/cho-b7h3-cell-bhc11101491","provider":"BioHippo","version":"1.0","type":"link"}