{"product_id":"cho-ccr8-cell-bhc11101492","title":"CHO-CCR8 cell","description":"Disclaimer: The prices displayed for cell lines are exclusively for not-for-profit customers. If you represent a commercial entity, please contact us for alternative pricing.The CHO-CCR8 cell line is a stable recombinant CHO (Chinese Hamster Ovary) cell line engineered to express the CCR8 receptor at a medium-high level, approximately 8,000 molecules per cell. This cell line was developed using advanced landing pad technology, ensuring precise and reproducible integration of the CCR8 gene at a specific, pre-validated genomic locus. CCR8, also known as CHEMR1 or CDw198, is a G protein-coupled receptor (GPCR) expressed on various immune cells, particularly regulatory T cells (Tregs). CCR8 plays a critical role in the immune suppression process within the tumor microenvironment, facilitating tumor cells' ability to evade immune detection. As such, targeting CCR8 has become a promising strategy in cancer immunotherapy to reduce Treg-mediated suppression and enhance anti-tumor immunity.\nThe expression of CCR8 in this cell line was confirmed using flow cytometry with a target-specific antibody, ensuring reliable and consistent receptor density across the cell population.\n\u003cp style=\"display:none\"\u003eSKU:BHC11101492\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950201270637,"sku":"305418","price":5000.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/cho-hd_1920x1920_29452378-9937-4200-92b0-746f8594eb7c.jpg?v=1769068991","url":"https:\/\/www.ebiohippo.com\/products\/cho-ccr8-cell-bhc11101492","provider":"BioHippo","version":"1.0","type":"link"}