{"product_id":"cho-her2-cell-bhc11101487","title":"CHO-HER2 cell","description":"Disclaimer: The prices displayed for cell lines are exclusively for not-for-profit customers. If you represent a commercial entity, please contact us for alternative pricing.The CHO-HER2-High cell line is a stable recombinant CHO (Chinese Hamster Ovary) cell line engineered to express the HER2 receptor at a high level, approximately 85,000 molecules per cell. This cell line was generated using an innovative landing pad technology that ensures the HER2 gene is integrated at a specific, pre-validated genomic locus, allowing for consistent and reliable expression. HER2, also known as ERBB2 or CD340, is a member of the epidermal growth factor receptor (EGFR) family and plays a crucial role in regulating cell growth and differentiation. It is well-known for its involvement in breast and ovarian cancers, where its overexpression is linked to increased tumor aggressiveness and poorer patient outcomes. HER2 is a key target for cancer therapies such as Trastuzumab (Herceptin) and Pertuzumab (Perjeta). This cell line is versatile, supporting both adherent and suspension culture conditions, with adherent cells exhibiting an epithelial-like morphology. The expression of CXCR7 in this cell line was confirmed using flow cytometry.\n\u003cp style=\"display:none\"\u003eSKU:BHC11101487\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950201598317,"sku":"305413H","price":5000.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/cho-hd_1920x1920_0417f2de-5b6b-4070-86b4-17db1050ece2.jpg?v=1769068993","url":"https:\/\/www.ebiohippo.com\/products\/cho-her2-cell-bhc11101487","provider":"BioHippo","version":"1.0","type":"link"}