{"product_id":"coenzyme-a-sodium-salt-bhb21200017","title":"Coenzyme A, Sodium salt","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\n\u003cp\u003eCoenzyme A, Sodium salt is a biochemical supplied by Coenza for use in enzymology and metabolic research. Available as Lyophilized powder, purity ≥ 98%, suitable for in vitro assays and pathway studies.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eAlso known as:\u003c\/em\u003e CoA Na2.\u003c\/p\u003e\n\u003ch2\u003eKey Elements and Design Rationale\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormula \/ MW \/ Purity:\u003c\/strong\u003e C21H33N7O16P3S · xNa · yH2O; 767.53 g\/mol (free acid basis); ≥ 98%. The Sodium salt form provides enhanced aqueous stability.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm \/ Solubility:\u003c\/strong\u003e Lyophilized powder; Soluble in water.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSynonyms:\u003c\/strong\u003e CoA Na2.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrigin:\u003c\/strong\u003e Biosynthetic synthesis.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eBiological Background\u003c\/h2\u003e\n\u003cp\u003eCoenzyme A (CoA) is an indispensable and ubiquitous metabolic cofactor for all organisms. It is synthesized in an evolutionarily conserved pathway by enzymatic conjugation of cysteine, pantothenate (Vitamin B5), and ATP. This unique chemical structure allows CoA to employ its highly reactive thiol group for diverse biochemical reactions. CoA is involved in approximately 9% of all metabolic pathways, including the tricarboxylic acid (TCA) cycle, fatty acid regulation, amino acid synthesis, and lipid metabolism (Leonardi et al., 2005; Daugherty et al., 2002).ApplicationsCoenzyme A Sodium Salt is widely used in metabolic research and biochemical studies due to its critical role in various enzymatic reactions and metabolic pathways. It is particularly valuable for investigating the mechanisms of energy production, lipid metabolism, and biosynthesis of key cellular components. Researchers utilize CoA Sodium Salt in studies related to cellular signaling, redox regulation, and metabolic diseases to understand better CoA's regulatory functions and its potential as a therapeutic target (Leonardi et al., 2005; Sibon \u0026amp; Strauss, 2016). Furthermore, its role in fatty acid oxidation and synthesi\u003c\/p\u003e\n\u003ch2\u003eResearch Relevance and Current Trends\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAcyl-CoA metabolism increasingly linked to histone acylation marks and epigenetic regulation in cancer and metabolic disease research.\u003c\/li\u003e\n\u003cli\u003eGrowing interest in short-chain fatty acid CoA thioesters as mediators of gut microbiome–host metabolic crosstalk.\u003c\/li\u003e\n\u003cli\u003eCoA-dependent enzymes investigated as drug targets in infectious disease and neurometabolic disorder research.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eCommon Research Applications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eEnzyme kinetics assays — direct substrate for acyltransferases, thiolases, and dehydrogenases.\u003c\/li\u003e\n\u003cli\u003eMetabolic flux analysis — isotope-labeled variants available for stable-isotope tracing.\u003c\/li\u003e\n\u003cli\u003eIn vitro pathway reconstitution for fatty acid β-oxidation, TCA cycle, or polyketide biosynthesis.\u003c\/li\u003e\n\u003cli\u003eBiochemical characterization of CoA-binding proteins by activity assays or binding measurements.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eNotes for Experimental Interpretation\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eCoA thioesters hydrolyze at neutral–alkaline pH; prepare working solutions fresh and keep on ice.\u003c\/li\u003e\n\u003cli\u003eDifferent salt forms share the same core structure — normalize concentrations using the free-acid MW when comparing across forms.\u003c\/li\u003e\n\u003cli\u003eThiol oxidation may occur upon air exposure; use under inert atmosphere or with reducing agents where appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Coenza","offers":[{"title":"10 mg","offer_id":53249725759853,"sku":"A-17-10MG","price":56.9,"currency_code":"USD","in_stock":true},{"title":"25 mg","offer_id":53249731264877,"sku":"A-17-25MG","price":93.8,"currency_code":"USD","in_stock":true},{"title":"50 mg","offer_id":53249731297645,"sku":"A-17-50MG","price":130.7,"currency_code":"USD","in_stock":true},{"title":"100 mg","offer_id":53249731330413,"sku":"A-17-100MG","price":188.1,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/c82f39_3faefec9ea714187b528a38f2d461624_mv2.png?v=1776855584","url":"https:\/\/www.ebiohippo.com\/products\/coenzyme-a-sodium-salt-bhb21200017","provider":"BioHippo","version":"1.0","type":"link"}