{"product_id":"corticosterone-eia-kit-bht11900003","title":"Corticosterone EIA Kit","description":"\u003cdiv class=\"bhp-desc\"\u003e\n\u003cstyle\u003e\n.bhp-desc{font-size:16px;color:#1a1a1a;line-height:1.7}\n.bhp-desc h2{font-size:18px;font-weight:700;color:#003366;margin:24px 0 10px;padding-bottom:6px;border-bottom:2px solid #003366}\n.bhp-desc p{margin:0 0 12px}\n.bhp-desc .bhp-spec-table{width:100%;border-collapse:collapse;margin:12px 0 18px}\n.bhp-desc .bhp-spec-table th{width:36%;text-align:left;padding:8px 12px;background:#e8f0fb;color:#003366;font-weight:600;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-spec-table td{padding:8px 12px;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-qc-badge{display:inline-block;background:#e6f4ea;color:#1a7a3c;border:1px solid #a8d5b5;border-radius:4px;padding:6px 14px;font-size:14px;font-weight:600}\n.bhp-desc .bhp-warning-box{background:#fff8e6;border-left:4px solid #e6a817;padding:10px 14px;margin:10px 0 14px;border-radius:0 4px 4px 0}\n.bhp-desc .bhp-cat-pill{display:inline-block;background:#003366;color:#fff;border-radius:20px;padding:3px 12px;font-size:13px;margin-bottom:10px}\n.bhp-desc .kit-comp-table{width:100%;border-collapse:collapse;margin:12px 0 18px;font-size:14px}\n.bhp-desc .kit-comp-table th{background:#003366;color:#fff;padding:7px 10px;text-align:left;border:1px solid #ccd9f0}\n.bhp-desc .kit-comp-table td{padding:7px 10px;border:1px solid #ccd9f0;vertical-align:top}\n.bhp-desc .kit-comp-table tr:nth-child(even) td{background:#f4f7fc}\n\u003c\/style\u003e\n\n\u003ch2\u003eScientific Background\u003c\/h2\u003e\n\u003cp\u003eCorticosterone (C₂₁H₃₀O₄) is the dominant glucocorticoid in rodents, synthesized by the adrenal cortex under ACTH stimulation and widely used as the primary model compound for studying hypothalamic–pituitary–adrenal (HPA) axis regulation and stress physiology. Unlike cortisol in humans, corticosterone is the principal endogenous ligand for both mineralocorticoid receptors (MR, high affinity) and glucocorticoid receptors (GR, lower affinity) in the rodent brain.\u003c\/p\u003e\n\u003cp\u003eChronic elevation of corticosterone has been shown to impair spatial memory and hippocampal long-term potentiation, alter sleep architecture, suppress neurogenesis in the dentate gyrus, and accelerate accumulation of phosphorylated α-synuclein in hypothalamic dopaminergic neurons—findings that directly link chronic stress physiology to Parkinson's disease pathology.\u003c\/p\u003e\n\u003cp\u003eCorticosterone measurement in fecal extracts enables minimally invasive, longitudinal HPA axis profiling in murine and avian research models, avoiding the confounding acute stress responses associated with blood collection. Its measurement is foundational in stress neurobiology, behavioral pharmacology, and corticosteroid-pathway drug development.\u003c\/p\u003e\n\n\u003ch2\u003eProduct Description\u003c\/h2\u003e\n\u003cp\u003e\u003cspan class=\"bhp-cat-pill\"\u003eStressXpress®\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eThe \u003cstrong\u003eCorticosterone EIA Kit\u003c\/strong\u003e (Cat. # SKT-205) from StressMarq Biosciences is a research-grade kit for quantitative Corticosterone measurement in Serum, EDTA Plasma, Heparin Plasma, Urine, Tissue Culture Media, Dried Fecal Samples. This kit employs a sandwich immunoassay principle with colorimetric TMB\/spectrophotometric readout on a standard 96-well microplate reader.\u003c\/p\u003e\n\n\u003ch2\u003eProduct Specifications\u003c\/h2\u003e\n\u003ctable class=\"bhp-spec-table\"\u003e\n\u003ctr\u003e\n\u003cth\u003eAnalyte \/ Target\u003c\/th\u003e\n\u003ctd\u003eCorticosterone\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eAssay Type\u003c\/th\u003e\n\u003ctd\u003eSandwich EIA (Enzyme Immunoassay)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eDetection Method\u003c\/th\u003e\n\u003ctd\u003eColorimetric (microplate spectrophotometry)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eSensitivity\u003c\/th\u003e\n\u003ctd\u003e18.6 pg\/ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eDetection Range\u003c\/th\u003e\n\u003ctd\u003e78.125–10,000 pg\/ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eCompatible Matrices\u003c\/th\u003e\n\u003ctd\u003eSerum, EDTA Plasma, Heparin Plasma, Urine, Tissue Culture Media, Dried Fecal Samples\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecies Reactivity\u003c\/th\u003e\n\u003ctd\u003eSpecies Independent\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eThroughput\u003c\/th\u003e\n\u003ctd\u003e39 samples in duplicate\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003ctr\u003e\n\u003cth\u003ePlatform\u003c\/th\u003e\n\u003ctd\u003eMicroplate (96-well)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eCatalog Number\u003c\/th\u003e\n\u003ctd\u003eSKT-205\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eStorage\u003c\/th\u003e\n\u003ctd\u003e4ºC and -20ºC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eTrademark\u003c\/th\u003e\n\u003ctd\u003eStressXpress®\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\n\u003ch2\u003eAssay Principle\u003c\/h2\u003e\n\u003cp\u003eThis kit uses a competitive or sandwich enzyme immunoassay (EIA) format—a microplate-based immunoassay technique functionally equivalent to ELISA. Corticosterone in the sample competes with enzyme-labeled conjugate for a limited number of antibody binding sites. Bound conjugate is detected colorimetrically via TMB substrate; absorbance is inversely proportional to the Corticosterone concentration, interpolated from a calibration curve (range: 78.125–10,000 pg\/ml).\u003c\/p\u003e\n\u003cp\u003eThe kit measures total Corticosterone and is fully validated for use in \u003cstrong\u003eSerum, EDTA Plasma, Heparin Plasma, Urine, Tissue Culture Media, Dried Fecal Samples\u003c\/strong\u003e. The Steroid Solid Extraction Protocol (where provided) enables reliable extraction from complex matrices such as dried fecal samples.\u003c\/p\u003e\n\n\u003ch2\u003eKit Components\u003c\/h2\u003e\n\u003ctable class=\"kit-comp-table\"\u003e\n\u003ctr\u003e\n\u003cth\u003eComponent #\u003c\/th\u003e\n\u003cth\u003eDescription\u003c\/th\u003e\n\u003cth\u003eQuantity \/ Volume\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSKC-205A\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eCoated Clear 96-Well Plate\u003c\/td\u003e\n\u003ctd\u003e1 Each\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSKC-205B\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eCorticosterone Standard\u003c\/td\u003e\n\u003ctd\u003e125 µl\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSKC-205C\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eStressXpress® Corticosterone Antibody\u003c\/td\u003e\n\u003ctd\u003e3 ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSKC-205D\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eStressXpress® Corticosterone Conjugate\u003c\/td\u003e\n\u003ctd\u003e3 ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSKC-205E\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAssay Buffer\u003c\/td\u003e\n\u003ctd\u003e28 ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSKC-205F\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eDissociation Reagent\u003c\/td\u003e\n\u003ctd\u003e1 ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSKC-205G\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eWash Buffer Concentrate\u003c\/td\u003e\n\u003ctd\u003e30 ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSKC-205H\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eTMB Substrate\u003c\/td\u003e\n\u003ctd\u003e11 ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSKC-205I\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eStop Solution\u003c\/td\u003e\n\u003ctd\u003e5 ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSKC-205J\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003ePlate Sealer\u003c\/td\u003e\n\u003ctd\u003e1 each\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\n\u003ch2\u003eQuality Control \u0026amp; Validation\u003c\/h2\u003e\n\u003cp\u003e\u003cspan class=\"bhp-qc-badge\"\u003e✓ Peer-Reviewed \u0026amp; Research Validated\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eEach lot is validated for sensitivity, intra-assay precision (CV \u0026lt;10%), and linearity of recovery. Products from the StressXpress® range cite published peer-reviewed literature for independent validation.\u003c\/p\u003e\n\n\u003ch2\u003eSafety \u0026amp; Regulatory\u003c\/h2\u003e\n\u003cdiv class=\"bhp-warning-box\"\u003e\n\u003cstrong\u003eResearch Use Only (RUO).\u003c\/strong\u003e Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.\u003c\/div\u003e\n\u003cp\u003eADR Classification: Non-hazardous. Shipping: cold-chain (blue ice). Harmonized Tariff Code: 3822.19.0030 (UNSPSC: 12352203). Country of Origin: Canada.\u003c\/p\u003e\n\n\u003c\/div\u003e","brand":"StressMarq Biosciences Inc.","offers":[{"title":"96 well","offer_id":53340031713645,"sku":"SKT-205-96","price":264.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/SKT-205_Corticosterone_EIA_Kit_Standard_Curve_Fig2-1.png?v=1782159108","url":"https:\/\/www.ebiohippo.com\/products\/corticosterone-eia-kit-bht11900003","provider":"BioHippo","version":"1.0","type":"link"}