{"product_id":"creatinine-serum-detection-kit-bht11900005","title":"Creatinine Serum Detection Kit","description":"\u003cdiv class=\"bhp-desc\"\u003e\n\u003cstyle\u003e\n.bhp-desc{font-size:16px;color:#1a1a1a;line-height:1.7}\n.bhp-desc h2{font-size:18px;font-weight:700;color:#003366;margin:24px 0 10px;padding-bottom:6px;border-bottom:2px solid #003366}\n.bhp-desc p{margin:0 0 12px}\n.bhp-desc .bhp-spec-table{width:100%;border-collapse:collapse;margin:12px 0 18px}\n.bhp-desc .bhp-spec-table th{width:36%;text-align:left;padding:8px 12px;background:#e8f0fb;color:#003366;font-weight:600;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-spec-table td{padding:8px 12px;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-qc-badge{display:inline-block;background:#e6f4ea;color:#1a7a3c;border:1px solid #a8d5b5;border-radius:4px;padding:6px 14px;font-size:14px;font-weight:600}\n.bhp-desc .bhp-warning-box{background:#fff8e6;border-left:4px solid #e6a817;padding:10px 14px;margin:10px 0 14px;border-radius:0 4px 4px 0}\n.bhp-desc .bhp-cat-pill{display:inline-block;background:#003366;color:#fff;border-radius:20px;padding:3px 12px;font-size:13px;margin-bottom:10px}\n.bhp-desc .kit-comp-table{width:100%;border-collapse:collapse;margin:12px 0 18px;font-size:14px}\n.bhp-desc .kit-comp-table th{background:#003366;color:#fff;padding:7px 10px;text-align:left;border:1px solid #ccd9f0}\n.bhp-desc .kit-comp-table td{padding:7px 10px;border:1px solid #ccd9f0;vertical-align:top}\n.bhp-desc .kit-comp-table tr:nth-child(even) td{background:#f4f7fc}\n\u003c\/style\u003e\n\n\u003ch2\u003eScientific Background\u003c\/h2\u003e\n\u003cp\u003eCreatinine, a non-protein nitrogenous waste product derived from the non-enzymatic breakdown of phosphocreatine in skeletal muscle, is continuously excreted by the kidneys through glomerular filtration with negligible tubular secretion or reabsorption at normal serum concentrations. This makes serum creatinine a cornerstone biomarker of glomerular filtration rate (GFR) estimation and a standard surrogate for renal function in clinical and preclinical settings.\u003c\/p\u003e\n\u003cp\u003eIn neuroscience research, serum creatinine measurements inform systemic health monitoring for rodent cohorts exposed to nephrotoxic pharmacological agents or undergoing chronic disease modeling. Elevated serum creatinine in rodent models correlates with accumulation of uremic toxins that potentiate neuroinflammation and contribute to hippocampal and cortical dysfunction.\u003c\/p\u003e\n\u003cp\u003eIts low intra-individual biological variability (\u0026lt;15% CV) makes creatinine an ideal internal reference for multi-timepoint longitudinal studies. Combined with BUN, GFR estimations can assess renal clearance of neurotoxic metabolites in chronic kidney disease and cardio-renal syndrome research.\u003c\/p\u003e\n\n\u003ch2\u003eProduct Description\u003c\/h2\u003e\n\u003cp\u003e\u003cspan class=\"bhp-cat-pill\"\u003eStressXpress®\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eThe \u003cstrong\u003eCreatinine Serum Detection Kit\u003c\/strong\u003e (Cat. # SKT-217) from StressMarq Biosciences is a research-grade kit for quantitative Creatinine measurement in Serum, Plasma. This kit employs a direct colorimetric detection principle with colorimetric TMB\/spectrophotometric readout on a standard 96-well microplate reader.\u003c\/p\u003e\n\n\u003ch2\u003eProduct Specifications\u003c\/h2\u003e\n\u003ctable class=\"bhp-spec-table\"\u003e\n\u003ctr\u003e\n\u003cth\u003eAnalyte \/ Target\u003c\/th\u003e\n\u003ctd\u003eCreatinine\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eAssay Type\u003c\/th\u003e\n\u003ctd\u003eDirect Quantitative Assay\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eDetection Method\u003c\/th\u003e\n\u003ctd\u003eColorimetric (microplate spectrophotometry)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eSensitivity\u003c\/th\u003e\n\u003ctd\u003e0.085 mg\/dl\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eDetection Range\u003c\/th\u003e\n\u003ctd\u003e0.5–4 mg\/dl\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eCompatible Matrices\u003c\/th\u003e\n\u003ctd\u003eSerum, Plasma\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecies Reactivity\u003c\/th\u003e\n\u003ctd\u003eHuman, Mouse, Rabbit, Rat, Sheep\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eThroughput\u003c\/th\u003e\n\u003ctd\u003e91 samples in duplicate\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003ctr\u003e\n\u003cth\u003ePlatform\u003c\/th\u003e\n\u003ctd\u003eMicroplate (96-well)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eCatalog Number\u003c\/th\u003e\n\u003ctd\u003eSKT-217\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eStorage\u003c\/th\u003e\n\u003ctd\u003e4ºC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eTrademark\u003c\/th\u003e\n\u003ctd\u003eStressXpress®\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\n\u003ch2\u003eAssay Overview\u003c\/h2\u003e\n\u003cp\u003eThis kit uses a direct colorimetric enzymatic reaction for quantitative Creatinine measurement without the need for sample pre-extraction. A calibrated standard (traceable to NIST reference material where applicable) is provided to construct a standard curve for interpolation. Results are read on a standard microplate spectrophotometer.\u003c\/p\u003e\n\u003cp\u003eCompatible sample matrices include: \u003cstrong\u003eSerum, Plasma\u003c\/strong\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eKit Components\u003c\/h2\u003e\n\u003ctable class=\"kit-comp-table\"\u003e\n\u003ctr\u003e\n\u003cth\u003eComponent #\u003c\/th\u003e\n\u003cth\u003eDescription\u003c\/th\u003e\n\u003cth\u003eQuantity \/ Volume\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSKC-217A\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eClear 96-Well Half Area Plates\u003c\/td\u003e\n\u003ctd\u003e2 Plates\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSKC-217B\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eCreatinine Standard\u003c\/td\u003e\n\u003ctd\u003e100 µl\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSKC-217C\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAssay Diluent\u003c\/td\u003e\n\u003ctd\u003e6 ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSKC-217D\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eStressXpress® Creatinine Reagent\u003c\/td\u003e\n\u003ctd\u003e20 ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\n\u003ch2\u003eQuality Control \u0026amp; Validation\u003c\/h2\u003e\n\u003cp\u003e\u003cspan class=\"bhp-qc-badge\"\u003e✓ Peer-Reviewed \u0026amp; Research Validated\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eEach lot is validated for sensitivity, intra-assay precision (CV \u0026lt;10%), and linearity of recovery. Products from the StressXpress® range cite published peer-reviewed literature for independent validation.\u003c\/p\u003e\n\n\u003ch2\u003eSafety \u0026amp; Regulatory\u003c\/h2\u003e\n\u003cdiv class=\"bhp-warning-box\"\u003e\n\u003cstrong\u003eResearch Use Only (RUO).\u003c\/strong\u003e Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.\u003c\/div\u003e\n\u003cp\u003eADR Classification: Non-hazardous. Shipping: cold-chain (blue ice). Harmonized Tariff Code: 3822.19.0030 (UNSPSC: 12352203). Country of Origin: Canada.\u003c\/p\u003e\n\n\u003c\/div\u003e","brand":"StressMarq Biosciences Inc.","offers":[{"title":"96 well x2","offer_id":53340031517037,"sku":"SKT-217-192","price":253.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/SKT-217_Creatinine_Serum_Detection_Kit_Standard_Curve_Fig2.png?v=1779020319","url":"https:\/\/www.ebiohippo.com\/products\/creatinine-serum-detection-kit-bht11900005","provider":"BioHippo","version":"1.0","type":"link"}