{"product_id":"cu43-protease-human-igg-specific-bhp21409882","title":"CU43 Protease (Human IgG Specific)","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eTarget identity:\u003c\/strong\u003e\u003cstrong\u003eHUMANIGGSPECIFIC\u003c\/strong\u003e is a enzyme. It is typically cytosolic, nuclear, or organelle-localized (depends on isoform).\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHUMANIGGSPECIFIC\u003c\/strong\u003e is provided as a recombinant protein reagent for \u003cstrong\u003eresearch use only\u003c\/strong\u003e. Recombinant proteins are commonly used as defined molecular inputs in biochemical and cell-free systems, enabling controlled interrogation of binding, activity, and pathway-relevant interactions.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eProtein identity context:\u003c\/strong\u003e HUMANIGGSPECIFIC (expression region CU43 Protease is cloned from Corynebacterium ulcerans and expressed in Mammalian cells.; approx. molecular weight 70.94 kDa).\u003c\/p\u003e\u003ch2\u003eBiological significance and function\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eHUMANIGGSPECIFIC\u003c\/strong\u003e supports biochemical transformations that can be read out as changes in substrate\/product balance or signaling intermediates. Recombinant enzymes enable controlled reconstitution experiments and mechanistic interrogation with defined inputs. This target is frequently explored in \u003cstrong\u003eMetabolism \u0026amp; Enzymology\u003c\/strong\u003e research contexts.\u003c\/p\u003e\u003ch2\u003eMolecular characteristics\u003c\/h2\u003e\u003cp\u003eKey molecular attributes can influence binding behavior, stability, and assay background—especially for multimeric, disulfide-rich, or PTM-dependent targets.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eExpression system:\u003c\/strong\u003e Mammalian Cells\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExpression region:\u003c\/strong\u003e CU43 Protease is cloned from Corynebacterium ulcerans and expressed in Mammalian cells.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular weight:\u003c\/strong\u003e 70.94 kDa\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e \u0026gt;90%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Liquid\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e 0.01M PBS, pH 7.4.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003ePost-translational considerations:\u003c\/strong\u003e Mammalian expression can support native-like folding, disulfide bond formation, and glycosylation. These features can be important for secreted proteins and receptor-binding interactions. For enzymes, cofactor binding state and oligomerization can also shape apparent activity in reconstituted assays.\u003c\/p\u003e\u003ch2\u003eStructural and biochemical features\u003c\/h2\u003e\u003cp\u003eEnzyme behavior can be influenced by oligomerization, cofactor state, and local microenvironment, which may change apparent kinetics in simplified assay formats.\u003c\/p\u003e\u003ch2\u003eExpression and purification strategy\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eExpression system:\u003c\/strong\u003e Mammalian Cells. Expression host selection can influence folding and PTM state, which may affect activity or binding in different assay formats.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePurification:\u003c\/strong\u003e Affinity-chromatography. Purification approach and formulation influence sample homogeneity and background signal in downstream biochemical measurements.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eEndotoxin consideration:\u003c\/strong\u003e Reported endotoxin level is Please contact with the lab for this information.; this parameter can matter when recombinant proteins are used in cell-based systems sensitive to innate immune activation.\u003c\/p\u003e\u003ch2\u003eResearch interpretation\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eResearch interpretation:\u003c\/strong\u003e Enzymatic readouts can reflect both abundance and catalytic state. Orthogonal measurements (substrate levels, product formation, and pathway markers) help clarify whether changes arise from expression, inhibition, or cofactor availability.\u003c\/p\u003e","brand":"Biohippo Inc","offers":[{"title":"100 ug","offer_id":53001947939181,"sku":"JN946011-100UG","price":478.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53001947971949,"sku":"JN946011-1MG","price":2878.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.ebiohippo.com\/products\/cu43-protease-human-igg-specific-bhp21409882","provider":"BioHippo","version":"1.0","type":"link"}