{"product_id":"deoxyhypusine-synthase-antibody-dhps-dhs-bha17122730","title":"Deoxyhypusine synthase Antibody \/ DHPS \/ DHS","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\u003cp\u003eDeoxyhypusine synthase is an enzyme that in humans is encoded by the DHPS gene. This gene encodes a protein that is required for the formation of hypusine, a unique amino acid formed by the posttranslational modification of only one protein, eukaryotic translation initiation factor 5A. The encoded protein catalyzes the first step in hypusine formation by transferring the butylamine moiety of spermidine to a specific lysine residue of the eukaryotic translation initiation factor 5A precursor, forming an intermediate deoxyhypusine residue. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.\u003c\/p\u003e\u003cp\u003eThis anti-Deoxyhypusine synthase antibody is supplied as Antigen affinity purified (Rabbit, Polyclonal (rabbit origin), Rabbit IgG, Unconjugated) and is designed to support common target-detection workflows after the on-page specifications.\u003c\/p\u003e\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTarget:\u003c\/strong\u003e Deoxyhypusine synthase\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Antigen affinity purified\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLocalization:\u003c\/strong\u003e Cytoplasmic, nuclear\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpecies reactivity:\u003c\/strong\u003e Human, Mouse, Rat\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eApplications (listed):\u003c\/strong\u003e WB, IHC-P, IF, FACS, Direct ELISA\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConjugate:\u003c\/strong\u003e Unconjugated\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClone and antibody class:\u003c\/strong\u003e Polyclonal (rabbit origin), Rabbit IgG\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eBecause antibody performance can depend on epitope context, sample preparation, and biological state, interpret signals using appropriate controls and orthogonal evidence when possible.\u003c\/p\u003e\u003ch2\u003eBiological background\u003c\/h2\u003e\u003cp\u003eDeoxyhypusine synthase is referenced in public gene\/protein resources (e.g., UniProt and NCBI Gene), which provide curated names\/synonyms, protein features, and pathway context. When designing assays, consider potential isoforms, post-translational modifications, and cell-type specific expression that may influence observed signal.\u003c\/p\u003e\u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eProfiling Deoxyhypusine synthase expression across model systems, perturbations, and time points to support mechanistic hypotheses.\u003c\/li\u003e\n\u003cli\u003eCombining antibody-based detection with multi-omics or imaging readouts to link Deoxyhypusine synthase signal with phenotype.\u003c\/li\u003e\n\u003cli\u003eUsing well-matched controls (isotype controls, genetic perturbations, or independent reagents) to strengthen interpretation of target-associated signal.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eCommon research applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eWB\u003c\/li\u003e\n\u003cli\u003eIHC-P\u003c\/li\u003e\n\u003cli\u003eIF\u003c\/li\u003e\n\u003cli\u003eFACS\u003c\/li\u003e\n\u003cli\u003eDirect ELISA\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eUse the listed applications as a starting point and tailor experimental design to your sample type and readout requirements.\u003c\/p\u003e\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpecificity considerations:\u003c\/strong\u003e closely related family members, isoforms, or PTMs can affect apparent specificity; confirm with independent approaches when critical.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eControls:\u003c\/strong\u003e include negative controls and, when feasible, genetic or pharmacologic perturbations to support target attribution in your system.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpecies and sample context:\u003c\/strong\u003e differences in sequence, expression, fixation, or extraction conditions can change signal behavior across models.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c!-- Sources (internal): - UniProt Knowledgebase — UniProt — https:\/\/www.uniprot.org\/ - NCBI Gene — NCBI — https:\/\/www.ncbi.nlm.nih.gov\/gene\/ - Ensembl Genome Browser — EMBL-EBI — https:\/\/www.ensembl.org\/ - Human Protein Atlas — SciLifeLab\/KTH — https:\/\/www.proteinatlas.org\/ - Gene Ontology — GO Consortium — https:\/\/geneontology.org\/ - Reactome Pathway Database — Reactome — https:\/\/reactome.org\/ - PubMed — NCBI — https:\/\/pubmed.ncbi.nlm.nih.gov\/ --\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.5mg\/ml if reconstituted with 0.2ml sterile DI water \/ 100 ug","offer_id":53045253079405,"sku":"RQ6469","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/get_image_803ee20e-549d-488a-ae1f-7fd092b11177.jpg?v=1771953549","url":"https:\/\/www.ebiohippo.com\/products\/deoxyhypusine-synthase-antibody-dhps-dhs-bha17122730","provider":"BioHippo","version":"1.0","type":"link"}