{"product_id":"ebola-virus-like-particles-ebov-zaire-bhv20900042","title":"Ebola Virus-like particles (EBOV)","description":"\u003cstyle\u003e\n.bhp-desc{font-size:16px;color:#1a1a1a;line-height:1.7}\n.bhp-desc h2{font-size:18px;font-weight:700;color:#003366;margin:24px 0 10px;padding-bottom:6px;border-bottom:2px solid #003366}\n.bhp-desc p{margin:0 0 12px}\n.bhp-desc .bhp-spec-table{width:100%;border-collapse:collapse;margin:12px 0 18px}\n.bhp-desc .bhp-spec-table th{width:36%;text-align:left;padding:8px 12px;background:#e8f0fb;color:#003366;font-weight:600;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-spec-table td{padding:8px 12px;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-warning-box{background:#fff8e6;border-left:4px solid #e6a817;padding:10px 14px;margin:10px 0 14px;border-radius:0 4px 4px 0}\n.bhp-desc .bhp-cat-pill{display:inline-block;background:#003366;color:#fff;border-radius:20px;padding:3px 12px;font-size:13px;margin-bottom:10px}\n\u003c\/style\u003e\n\u003cdiv class=\"bhp-desc\"\u003e\n\u003ch2\u003eScientific Background\u003c\/h2\u003e\n\u003cp\u003eZaire Ebola virus (EBOV) is the most lethal species of the Ebolavirus genus, responsible for multiple large outbreaks including the 2014–2016 West Africa epidemic. EBOV is classified as a BSL-4 pathogen, with case fatality rates of up to 90% in untreated patients. The viral glycoprotein (GP) mediates cell entry via macropinocytosis and NPC1-dependent membrane fusion. Safe surrogate systems for studying EBOV entry and evaluating anti-EBOV countermeasures are critical for biodefense and therapeutic development.\u003c\/p\u003e\n\u003ch2\u003eProduct Description\u003c\/h2\u003e\n\u003cp\u003e\u003cspan class=\"bhp-cat-pill\"\u003eFilovirus\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eThis HA-EBOV VLP is a hybrid alpha-pseudovirus assembled from Ebola Virus Zaire structural proteins (GP, VP40, NP) with an alphavirus-derived reporter RNA payload. BSL-2 safe and ready to use for studying viral entry. Available with Firefly luciferase, GFP, or RFP reporter.\u003c\/p\u003e\n\u003ch2\u003eProduct Specifications\u003c\/h2\u003e\n\u003ctable class=\"bhp-spec-table\"\u003e\n\u003ctr\u003e\n\u003cth\u003eCatalog Number\u003c\/th\u003e\n\u003ctd\u003e0571-PP-001\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eVirus Strain\u003c\/th\u003e\n\u003ctd\u003eZaire\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eStructural Proteins\u003c\/th\u003e\n\u003ctd\u003eGP (glycoprotein), VP40 (matrix protein), NP (nucleoprotein)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eReporter Payload\u003c\/th\u003e\n\u003ctd\u003eAlphavirus-derived self-replicating RNA encoding Firefly Luciferase, GFP, or RFP\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eParticle Type\u003c\/th\u003e\n\u003ctd\u003eSingle-cycle alpha-pseudovirus (BSL-2 safe)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eForm\u003c\/th\u003e\n\u003ctd\u003eLiquid\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eSize\u003c\/th\u003e\n\u003ctd\u003e1X Concentrated: 25 × 200 µL (~100 wells per 96-well plate)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eStorage\u003c\/th\u003e\n\u003ctd\u003e-80°C. Avoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eApplications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eEbola pseudovirus transduction of target cells for viral entry and functional studies\u003c\/li\u003e\n\u003cli\u003eRapid anti-Ebola drug and entry inhibitor screening\u003c\/li\u003e\n\u003cli\u003eRapid anti-Ebola neutralizing antibody screening and IC50 determination\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSafety \u0026amp; Handling\u003c\/h2\u003e\n\u003cdiv class=\"bhp-warning-box\"\u003e\n\u003cstrong\u003eResearch Use Only (RUO).\u003c\/strong\u003e Single-cycle BSL-2 safe pseudovirus. Not for human or veterinary use. Commercial use requires written approval from Integrated BioTherapeutics, LLC.\u003c\/div\u003e\n\u003c\/div\u003e","brand":"IBT Bioservices","offers":[{"title":"Luciferase \/ 1x Conc. 25 x 200uL (~100 wells)","offer_id":53402776174957,"sku":"0571-PP-001-LUC-1X","price":4520.0,"currency_code":"USD","in_stock":true},{"title":"GFP \/ 1x Conc. 25 x 200uL (~100 wells)","offer_id":53402776207725,"sku":"0571-PP-001-GFP-1X","price":4520.0,"currency_code":"USD","in_stock":true},{"title":"RFP \/ 1x Conc. 25 x 200uL (~100 wells)","offer_id":53402776240493,"sku":"0571-PP-001-RFP-1X","price":4520.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Group-2106_09575551-98b8-452e-a7a1-69af137c815a.png?v=1780516436","url":"https:\/\/www.ebiohippo.com\/products\/ebola-virus-like-particles-ebov-zaire-bhv20900042","provider":"BioHippo","version":"1.0","type":"link"}