{"product_id":"eif2ak1-2-3-4-quadruple-knockout-overexpressing-perk-mef-cell-line-eif2ak-4ko-perk-bhc10923119","title":"EIF2AK1\/2\/3\/4 Quadruple Knockout Overexpressing PERK MEF Cell Line (EIF2AK 4KO+PERK)","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\n\u003cp\u003eEIF2AK1\/2\/3\/4 Quadruple Knockout Overexpressing PERK MEF Cell Line (EIF2AK 4KO+PERK) is a engineered cell line supplied in cell format.\u003c\/p\u003e\n\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\n\u003cstrong\u003eModel identity:\u003c\/strong\u003e EIF2AK1\/2\/3\/4 Quadruple Knockout Overexpressing PERK MEF Cell Line (EIF2AK 4KO+PERK) is supplied as an engineered cell line.\u003c\/li\u003e\u003c\/ul\u003e\n\u003cp\u003eThis cell-based model is generally used in cell biology, phenotype comparison, and assay development studies.\u003c\/p\u003e\n\u003ch2\u003eBiological background\u003c\/h2\u003e\n\u003cp\u003eThis model supports studies in cell biology, phenotype comparison, and assay development. It can be used to examine morphology, growth behavior, and experimental responses in cultured cells.\u003c\/p\u003e\n\u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eEngineered cell lines are widely used for reporter-based readouts, perturbation studies, and assay optimization in reproducible culture systems.\u003c\/li\u003e\n\u003cli\u003eReporter or transgene-bearing models are often compared with matched parental or control cells to interpret signal changes in context.\u003c\/li\u003e\n\u003cli\u003eExpression trends are typically evaluated alongside passage number, selection pressure, and baseline growth behavior.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eCommon research applications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eRoutine expansion and maintenance of a defined cell model for downstream in vitro experiments.\u003c\/li\u003e\n\u003cli\u003ePhenotype, signaling, or marker-expression studies performed under standardized culture conditions.\u003c\/li\u003e\n\u003cli\u003eCell-based assay development in which passage number, growth surface, and medium composition are tracked as experimental variables.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eChanges in morphology, growth rate, viability, or reporter signal are typically interpreted together with passage history, culture matrix, and the specified growth conditions for the model.\u003c\/p\u003e\n\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eMorphology, doubling behavior, and reporter or marker output can shift with passage number, substrate choice, and medium composition; these variables should be recorded alongside experimental readouts.\u003c\/li\u003e\n\u003cli\u003eMatched controls such as parental cells, untreated cultures, or parallel cultures maintained under identical conditions help distinguish background effects from biology of interest.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"font-size:0.85em;color:#555555;border-top:1px solid #e0e9e9;padding-top:10px;margin-top:20px;\"\u003e\u003cstrong\u003eMaterial Citation:\u003c\/strong\u003e If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. T3614\u003c\/p\u003e","brand":"Applied Biological Materials (abm) Inc.","offers":[{"title":"1x10\u003csup\u003e6\u003c\/sup\u003e cells \/ 1.0 ml","offer_id":53180550578541,"sku":"T3614","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/iVUoBaJlh83VRXb06jWkoxbowBx53HVhXLrssO2r.png?v=1774957880","url":"https:\/\/www.ebiohippo.com\/products\/eif2ak1-2-3-4-quadruple-knockout-overexpressing-perk-mef-cell-line-eif2ak-4ko-perk-bhc10923119","provider":"BioHippo","version":"1.0","type":"link"}