{"product_id":"elikine-human-il-10-elisa-kit-bhe13710160","title":"EliKine™ Human IL-10 ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eEliKine™ Human IL-10 ELISA Kit has high sensitivity and excellent specificity for detection of Human IL-10. No significant cross-reactivity or interference between Human IL-10 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eThe protein encoded by IL-10 gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in IL-10 gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338663813485,"sku":"KTE6019-48T","price":189.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338910032237,"sku":"KTE6019-96T","price":289.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.ebiohippo.com\/products\/elikine-human-il-10-elisa-kit-bhe13710160","provider":"BioHippo","version":"1.0","type":"link"}