{"product_id":"fo-1-mel-cls-1-cell-bhc11100078","title":"FO-1 (MEL-CLS-1) cell","description":"The FO-1 cell line, also known as MEL-CLS-1, is a human amelanotic melanoma line derived from a metastatic site, specifically the iliac lymph node of a Caucasian patient. This cell line was established from a xenograft, further ensuring its utility in research focused on metastatic melanoma. Amelanotic melanoma, from which FO-1 originates, is characterized by the absence of melanin pigment, making it particularly valuable for studying melanoma subtypes that lack the typical pigmentation associated with these tumors.\n\nThe FO-1 cell line exhibits a doubling time of approximately 38 hours, particularly noted at the 49th passage. This relatively fast growth rate makes it suitable for experiments requiring rapid cell proliferation. FO-1 cells are known for their differential sensitivity to various treatments, including their responsiveness to the differentiating and antiproliferative effects of interferon-beta (IFN-β) and 12-O-tetradecanoyl-phorbol-13-acetate (TPA), making them a critical model for studying the modulation of melanoma-associated antigens and HLA antigen expression under various experimental conditions.\n\u003cp style=\"display:none\"\u003eSKU:BHC11100078\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950203924845,"sku":"300175","price":800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/mel-cls-1-_282_29_1920x1920_9c6cb47a-d97d-4ce4-a726-648389137078.jpg?v=1769069022","url":"https:\/\/www.ebiohippo.com\/products\/fo-1-mel-cls-1-cell-bhc11100078","provider":"BioHippo","version":"1.0","type":"link"}