{"product_id":"ftcd-human-bhz11000509","title":"FTCD Human","description":"\u003cdiv class=\"bhp-desc\"\u003e\n\u003ch3 style=\"color:#1a5c58;margin:12px 0 4px\"\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eFormiminotransferase Cyclodeaminase Human Recombinant\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"bhp-desc\"\u003e\n\u003ch3 style=\"color:#1a5c58;margin:12px 0 4px\"\u003eOverview\u003c\/h3\u003e\n\u003cp\u003eFormiminotransferase cyclodeaminase is an enzyme which catalyzes the conversion of formiminoglutamateand tetrahydrofolateinto formiminotetrahydrofolateand glutamate.Formiminotransferase cyclodeaminase, a bifunctional enzyme of tetrahydrofolate synthesis, is the target antigen of anti-LC1 (liver cytosol antigen type 1) autoantibodies. Presence of LC1 autoantibodies is a marker for type 2 autoimmune hepatitis (for which anti-LKM 1\/cytochrome P450 2D6 autoantibodies are a further marker).Serum LC1 autoantibody concentrations appear to fluctuate in parallel with aminotransferase levels, a particularly intriguing observation that suggests a possible role of LC1 autoreactivity in the pathogenic mechanism leading to hepatocyte injury.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"bhp-desc\"\u003e\n\u003ch3 style=\"color:#1a5c58;margin:12px 0 4px\"\u003eSpecifications\u003c\/h3\u003e\n\u003ctable style=\"width:100%;border-collapse:collapse;font-size:0.92em\"\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align:left;padding:4px 8px;background:#e8f4f3;width:180px;font-weight:bold\"\u003ePurity\u003c\/th\u003e\n\u003ctd style=\"padding:4px 8px\"\u003eGreater than 95% as determined by SDS-PAGE.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align:left;padding:4px 8px;background:#e8f4f3;width:180px;font-weight:bold\"\u003eFormulation\u003c\/th\u003e\n\u003ctd style=\"padding:4px 8px\"\u003eFTCD is supplied in 16mM HEPES buffer pH-7.6, 240mM sodium chloride, and 20% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align:left;padding:4px 8px;background:#e8f4f3;width:180px;font-weight:bold\"\u003eStorage\u003c\/th\u003e\n\u003ctd style=\"padding:4px 8px\"\u003eStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°Cfor longer periods of time. Avoid multiple freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align:left;padding:4px 8px;background:#e8f4f3;width:180px;font-weight:bold\"\u003eExpression System\u003c\/th\u003e\n\u003ctd style=\"padding:4px 8px\"\u003eSf9 insect cells.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5µg","offer_id":53340109046125,"sku":"ENZ-302-5µg","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":53340152136045,"sku":"ENZ-302-20µg","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":53340152168813,"sku":"ENZ-302-1mg","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ftcd-hunan-ENZ-302.png?v=1782158443","url":"https:\/\/www.ebiohippo.com\/products\/ftcd-human-bhz11000509","provider":"BioHippo","version":"1.0","type":"link"}