{"product_id":"gabarapl2-antibody-gamma-aminobutyric-acid-receptor-associated-protein-like-2-bha17136312","title":"GABARAPL2 Antibody \/ Gamma-aminobutyric acid receptor-associated protein-like 2","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\u003cp\u003eGABARAPL2 Antibody \/ Gamma-aminobutyric acid receptor-associated protein-like 2 is a anti-GABARAPL2 Rabbit antibody Recombinant Rabbit Monoclonal clone 17G90 supplied in Purified format. Recommended for workflows such as Western blot (WB), IHC-P with listed reactivity in Human, Mouse, Rat. Reported localization: Cytoplasm.\u003c\/p\u003e\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTarget:\u003c\/strong\u003e GABARAPL2\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntibody details:\u003c\/strong\u003e Rabbit, Recombinant Rabbit Monoclonal, clone 17G90, isotype Rabbit IgG\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Purified\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eApplications (as listed):\u003c\/strong\u003e WB, IHC-P\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eBiological background\u003c\/h2\u003e\u003cdiv\u003eGamma-aminobutyric acid receptor-associated protein-like 2 (GABARAPL2) is a ubiquitin-like protein involved in autophagy, intracellular trafficking, and receptor transport. It plays a role in the expansion of autophagosomal membranes and the delivery of cargo to lysosomes for degradation. GABARAPL2 also participates in the regulation of GABA receptor trafficking, influencing synaptic transmission.    \u003cp\u003eGABARAPL2 is expressed in various tissues and is linked to cellular processes such as protein turnover, stress responses, and immune regulation. Dysregulation of GABARAPL2 has been associated with neurological disorders, cancer, and other diseases involving impaired autophagy. Studying GABARAPL2 function helps elucidate the molecular mechanisms of protein homeostasis and membrane dynamics. \u003c\/p\u003e\n\u003cp\u003eUsing a high-quality GABARAPL2 antibody enables sensitive and specific detection in applications including western blot, immunohistochemistry, and immunofluorescence. A GABARAPL2 antibody from\u003c\/p\u003e\n\u003c\/div\u003e\u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eConnecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).\u003c\/li\u003e\n\u003cli\u003eConsidering isoforms and post-translational regulation when interpreting protein-level changes.\u003c\/li\u003e\n\u003cli\u003eComparing results across species and model systems with matched controls.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eCommon research applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eWestern blotting:\u003c\/strong\u003e compare relative abundance and activation-state changes across conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmunohistochemistry:\u003c\/strong\u003e map target signal in tissue context and compare regions\/phenotypes.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eInterpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.\u003c\/p\u003e\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eSignal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.\u003c\/li\u003e\n\u003cli\u003eSpecies differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eAntibody notes:\u003c\/strong\u003e Monoclonal antibodies provide a defined epitope recognition profile that can support consistent comparisons across experiments.\u003c\/p\u003e\u003c!-- Sources (internal): - UniProt search — UniProt — https:\/\/www.uniprot.org\/uniprotkb?query=GABARAPL2 - NCBI Gene search — NCBI — https:\/\/www.ncbi.nlm.nih.gov\/gene\/?term=GABARAPL2 - Ensembl search — Ensembl — https:\/\/www.ensembl.org\/Multi\/Search\/Results?q=GABARAPL2 - Human Protein Atlas search — HPA — https:\/\/www.proteinatlas.org\/search\/GABARAPL2 - PubMed (review) — NLM — https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=GABARAPL2+review --\u003e","brand":"NSJ Bioreagents","offers":[{"title":"Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg\/ml BSA \/ 100 ul","offer_id":53047325065581,"sku":"RQ8893","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/get_image_962df1f9-04a6-46f6-ae81-6e23739863a2.jpg?v=1772019442","url":"https:\/\/www.ebiohippo.com\/products\/gabarapl2-antibody-gamma-aminobutyric-acid-receptor-associated-protein-like-2-bha17136312","provider":"BioHippo","version":"1.0","type":"link"}