{"product_id":"gst-antibody-bha11906091","title":"GST Antibody","description":"\u003cp\u003eGlutathione S-transferases (GSTs) are a family of detoxifying enzymes that play a crucial role in cellular defense against oxidative stress. By catalyzing the conjugation of glutathione to a wide range of electrophilic compounds, GSTs help neutralize reactive oxygen species (ROS) and prevent cellular damage.\u003c\/p\u003e\n\n\u003cp\u003eIn the context of neurodegenerative diseases, GSTs are increasingly recognized for their neuroprotective functions. Oxidative stress is a key pathological feature in disorders such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis (ALS). GSTs mitigate this stress by detoxifying lipid peroxidation products and other neurotoxic metabolites, thereby preserving neuronal integrity.\u003c\/p\u003e\n\n\u003cp\u003eSeveral GST isoforms are expressed in the brain, and their expression levels are often altered in neurodegenerative conditions. Polymorphisms in GST genes have also been linked to increased susceptibility to neurodegeneration, suggesting a genetic component to their protective role.\u003c\/p\u003e\n\n\u003cp\u003eBeyond detoxification, GSTs may influence cell signaling pathways involved in inflammation, apoptosis, and mitochondrial function—processes that are dysregulated in neurodegeneration. As such, GSTs are being explored as potential biomarkers and therapeutic targets for early intervention and disease modification in neurodegenerative disorders.\u003c\/p\u003e","brand":"StressMarq Biosciences Inc.","offers":[{"title":"100 ug \/ Unconjugated","offer_id":53040792273261,"sku":"SMC-549D","price":337.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ ATTO 390","offer_id":53040862724461,"sku":"SMC-549D-A390","price":392.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ ATTO 488","offer_id":53040862757229,"sku":"SMC-549D-A488","price":391.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ ATTO 594","offer_id":53040862789997,"sku":"SMC-549D-A594","price":391.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ APC","offer_id":53040862822765,"sku":"SMC-549D-APC","price":390.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ BI","offer_id":53040862855533,"sku":"SMC-549D-BI","price":386.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ FITC","offer_id":53040862888301,"sku":"SMC-549D-FITC","price":381.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ HRP","offer_id":53040862921069,"sku":"SMC-549D-HRP","price":377.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ PCP","offer_id":53040862953837,"sku":"SMC-549D-PCP","price":390.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ RPE","offer_id":53040862986605,"sku":"SMC-549D-RPE","price":388.0,"currency_code":"USD","in_stock":true},{"title":"12 ug \/ Unconjugated","offer_id":53040863019373,"sku":"SMC-549S","price":45.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/SMC-549_GST_Antibody_3E2_WB_Schistosoma-japonicum_Purified-GST_1.png?v=1771832151","url":"https:\/\/www.ebiohippo.com\/products\/gst-antibody-bha11906091","provider":"BioHippo","version":"1.0","type":"link"}