{"product_id":"hek293-folr1-cell-bhc11101499","title":"HEK293-FOLR1 cell","description":"Disclaimer: The prices displayed for cell lines are exclusively for not-for-profit customers. If you represent a commercial entity, please contact us for alternative pricing.The HEK293-FOLR1 cell line is a stable recombinant HEK293 cell line engineered to express the FOLR1 receptor at a medium-high level, approximately 15,000 molecules per cell. This cell line was developed using inscreenex's landing pad technology, ensuring precise and reproducible integration of the FOLR1 gene at a specific, pre-validated genomic locus. FOLR1, also known as Folate Receptor Alpha (FRα) or FBP, is a GPI-anchored membrane protein with a strong affinity for folate, facilitating its transport into cells. FOLR1 is markedly overexpressed in certain cancers, such as ovarian, breast, and non-small cell lung cancers, making it a significant target for immuno-oncology therapies, including CAR T cell therapies and bispecific antibodies.The expression of FOLR1 in this cell line was confirmed using flow cytometry with a target-specific antibody, ensuring reliable and consistent receptor density across the cell population.\n\u003cp style=\"display:none\"\u003eSKU:BHC11101499\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950205825389,"sku":"305425","price":5000.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/hek293-hd_1920x1920_4fb0dd71-9989-40e5-b59b-30c18df936e8.jpg?v=1769069045","url":"https:\/\/www.ebiohippo.com\/products\/hek293-folr1-cell-bhc11101499","provider":"BioHippo","version":"1.0","type":"link"}